胸液α2-球蛋白与白蛋白比值在胸腔积液鉴别诊断中的价值

目的探讨α2球蛋白对结核性和癌性胸腔积液的鉴别诊断价值。方法分别对94例胸腔积液患者的胸液(结核性积液43例,癌性积液51例)进行蛋白电泳分析,检测白蛋白和α2球蛋白,计算α2-球蛋白与白蛋白比值。结果结核组α2球蛋白高于癌性组,差异有显著性(P<0.05);结核组α2-球蛋白与白蛋白比值低于恶性组,差异具有高度显著性(P<0.01)。结论胸腔积液α2球蛋白及α2-球蛋白与白蛋白比值检测有助于结核性与癌性胸腔积液的鉴别诊断。

Diagnostic value of ratio of α-2 global protein and albumen in the differentiation of pleural effusion

Objective To study the diagnostic value of the ratio of α-2 global protein and albumen in differentiating tuberculosis from malignant tumor pleural effusion.Methods 94 patients with pleural effusion,which included 43 cases of tuberculosis and 51 cases of malignant pleural effusion,were examined to detect α-2 global protein and albumen through protein electrophoresis.Results The levels of α-2 global protein was obviously higher in the tuberculosis pleural effusion group than in the malignant tumor pleural effusion group（P〈0.05）,and the ratio of α-2 global protein and albumen was lower in the tuberculosis group than in the malignant tumor group（P〈0.01）.Conclusion The detection of α-2 global protein and the ratio of α-2 global protein and albumen in patients with pleural effusion is helpful for differentiating tuberculosis from malignant tumor pleural effusion.