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Fisher成分分析法用于决明子化学指纹特征相似性研究
引用本文:鄢海燕,邹纯才.Fisher成分分析法用于决明子化学指纹特征相似性研究[J].药物分析杂志,2012(8):1417-1421.
作者姓名:鄢海燕  邹纯才
作者单位:皖南医学院药学系
摘    要:目的:探求Fisher成分分析法用于大、小决明子化学指纹特征相似的研究,为大、小决明子的分类提供依据。方法:对获得的指纹图谱进行数字化处理并得到大、小决明子的标准指纹图谱,然后用Fisher成分分析法提取大、小决明子化学指纹图谱中的隐含化学特征,对大、小决明子进行质量模式分类,并与主成分分析法及标准图谱法进行分类效果对比研究。结果:Fisher成分分析法能更好地表征大、小决明子的化学模式特征,分类准确性高。结论:根据Fisher成分分析法可识别大、小决明子的化学指纹特征的内在差异,可用于鉴别中药材真伪。

关 键 词:Fisher成分分析法  决明子  化学成分指纹特征相似性  大黄酚参照峰

Application of Fisher component analysis in the research of chemical fingerprint feature similarities of Semen Cassiae
YAN Hai-yan,ZOU Chun-cai.Application of Fisher component analysis in the research of chemical fingerprint feature similarities of Semen Cassiae[J].Chinese Journal of Pharmaceutical Analysis,2012(8):1417-1421.
Authors:YAN Hai-yan  ZOU Chun-cai
Institution:(Department of Pharmacy,Wannan Academy of Medical,Wuhu 241002,China)
Abstract:Objective:To explore whether Fisher component analysis can be used in the research of chemical fingerprint feature similarities of Semen Cassiae Obtasefolia and Semen Cassia Tora,and to provide a basis for the classification of Semen Cassiae.Methods:The standard fingerprints of Semen Cassiae obtasefolia and Semen Cassia tora were obtained by digitizing their original fingerprints.Next,the chemical fingerprint features of Semen Cassiae obtasefolia and Semen Cassia tora were extracted Fisher component analysis.Then,Semen Cassiae obtasefolia and Semen Cassia tora were classified by quality model.The classification results were compared with those classified by quality model.The classification results were compared with those classified by principal component analysis and standard atlas analysis.Results:Fisher component analysis could show the chemical pattern feature of Semen Cassiae obtasefolia and Semen Cassia tora more effectively with high classification precision.Conclusion:Fisher component analysis can be used in identifying the internal differences of Semen Cassiae obtasefolia and Semen Cassia tora in chemical fingerprint features and the authenticity of Chinese medicinal.
Keywords:Fisher component analysis  Semen Cassiae  chemical constituent fingerprint feature similarity  chrysophanol reference peak
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