| 聚合酶链反应检测血清中HBV DNA的临床意义 |
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| 引用本文： | 余竹元,汤钊猷,周铬,邵力.聚合酶链反应检测血清中HBV DNA的临床意义[J].复旦学报(医学版),1993(1). |
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| 作者姓名： | 余竹元 汤钊猷 周铬 邵力 |
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| 作者单位： | 上海医科大学肝癌研究所
(余竹元，汤钊猷，周铬)，上海市第一人民医院中心实验室(邵力) |
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| 摘 要： | 我们开发了一种敏感又快速的方法,以检测低水平乙型肝炎病毒(HBV)感染。通过聚合酶链反应(PCR)检测了12例慢性肝炎和52例肝癌病人血清中的HBV DNA。将PCR分析结果与常规血清标志物相比较,并评价检测血清中HBV DNA的临床意义。
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| 关 键 词： | 乙型肝炎病毒 聚合酶链反应 慢性乙型肝炎 肝细胞癌(肝癌) |
THE CUNICAL SIGNIFICANCE OF DETECTABLE HBV DNA IN SERUM BY POLYMERASE CHAIN REACTION |
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| Yu Zhu-Yuan,Tang Zhao-You,Zhou Ge,Shao Li.THE CUNICAL SIGNIFICANCE OF DETECTABLE HBV DNA IN SERUM BY POLYMERASE CHAIN REACTION[J].Fudan University Journal of Medical Sciences,1993(1). |
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| Authors: | Yu Zhu-Yuan Tang Zhao-You Zhou Ge Shao Li |
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| Abstract: | We have developed a sensitive und rapid method to detect low-level hepatitis B virus (HBV) infection. HBV DNA was detected by polymerase chain reaction (FOR) in sera from 12 patients with chronic hepatitis B and 52 patients with hepatocellular carcinoma. The findings from FOR analyses were compared with conventional serological markers to assess the clinical significance of detectable HBV DNA in serum. |
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| Keywords: | hepatitis B virus polymerase chain reaction chronic hepatitis B hepatocellular carcinoma |
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