氯乙烯作业工人恶性肿瘤发病情况的流行病学调查

对全国12个城市的13个聚氯乙烯制造工人中5459名氯乙烯作业工人和6461名对照厂工人进行了从投产到1989年12月31日为止的恶性肿瘤发病情况的回顾性和前瞻性队列调查。结果表明,男工接触组肝癌的发病率、死亡率均显著高于对照组,男性肝癌的死亡率也显著高于我国中等城市男性肝癌的死亡率。在恶性肿瘤的分类构成中,接触组男工的肝癌居首位。接触组男工肝癌的发病年龄比对照组显著提前。

EPIDEMIOLOGICAL INVESTIGATION ON MALIGANANT TUMORS IN WORKERS EXPOSED TO VINYL CHLORIDE

Thirteen polyvinyl chloride manufacturing plants of 12 cities in China were investigated.This survey covered 5459workers exposed to vinyl chloride and 6461 workers unexposed to it.The investigation was carried out in retrospective andprospective cohort study,recorded from year of starting production to December 31,1989.The results showed that theincidence and mortality of liver cancer in male workers exposed to vinyl chloride were significantly higher than those of thecontrol group.The mortality of liver cancer in male workers exposed to vinyl chloride also was significantly higher than that ofthe male population in the middle cities in China.Among malignant tumors,liver cancer ranked first in male workers exposedto vinyl chloride.The average age for persons who were diagnosed as liver cancer in male workers was significantly youngerthan that of the control group.