| 大面积烧伤患者早期红细胞变形能力与红细胞膜胆固醇、钠-钾ATP酶的关系 |
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| 引用本文： | 陶绍能,李小宁,崔凡,吕大伦.大面积烧伤患者早期红细胞变形能力与红细胞膜胆固醇、钠-钾ATP酶的关系[J].现代检验医学杂志,2001,16(1):19-20. |
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| 作者姓名： | 陶绍能 李小宁 崔凡 吕大伦 |
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| 作者单位： | 1. 皖南医学院附属医院检验科
2. 皖南医学院附属医院烧伤外科, |
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| 基金项目： | 本课题受皖医中青年科研基金资助(基金编号99WK013)。 |
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| 摘 要： | 目的 研究大面积烧伤患者早期红细胞变形能力与红细胞膜胆固醇、钠钾ATP酶的变化。探讨其在大面积烧伤早期中的关系。方法 采用核孔滤膜法测定红细胞变形性，使用化学修饰电极测定红细胞膜胆固醇，应用定磷法测定红细胞膜钠-钾ATP酶。结果 47例大面积烧伤患者早期红细胞变形性低于60例正常对照组(P＜0.01)，红细胞膜胆固醇、钠-钾ATP酶均高于正常对照组(P＜0.01)，且红细胞膜胆固醇、钠钾ATP酶与红细胞变形性呈负相关(r
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| 关 键 词： | 烧伤 红细胞变形性 胆固醇 红细胞膜 钠-钾ATP酶 |
| 文章编号： | 1005-1716(2001)01-019-02 |
| 修稿时间： | 2000年9月30日 |
Investigation of the
Relationship Between Red Cell Defermatility (RCD)in Early Stage of Great Area Burns
Patients with Erythrocyte Membrane Cholesterol and Na+-K+ Exchanging ATPase |
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| TAO Shao neng ,LI Xiao ning ,CUI Fan ,LU Da lun.Investigation of the
Relationship Between Red Cell Defermatility (RCD)in Early Stage of Great Area Burns
Patients with Erythrocyte Membrane Cholesterol and Na+-K+ Exchanging ATPase[J].Journal of Modern Laboratory Medicine,2001,16(1):19-20. |
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| Authors: | TAO Shao neng LI Xiao ning CUI Fan LU Da lun |
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| Institution: | TAO Shao neng 1,LI Xiao ning 1,CUI Fan 1,LU Da lun 2 |
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| Abstract: | Objective To investigate the relationship between red cell defermatility in early stage of great area burns patients with Membrane Cholesterol and Na -K Exchanging ATPase.Methods Use percolate to measure the index of red cell defermatility.Use chemically modified electrode to measure the Erythrocyte membrane cholesterol and use detecting pi to measure the Na -K exchanging ATPase.Results Erythrocyte membrane cholesterol and Na -K exchanging ATPase in early stage of great area burn are always higher than normal comparison ( P <0 01),and Red cell defermatility is lower than normal comparison ( P >0 01).Erythrocyte membrane cholesterol and Na -K exchanging ATPase are negative correlation with Red cell defermatility( r cho =-0 871, r ATPase =-0 801).Conclusion The Erythrocyte membrane cholesterol and Na -K exchanging ATPase are important reasons of the index of Red cell defermatility. |
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| Keywords: | Burn Red cell defermatility Cholesterol Erythrocyte membrane Na K exchanging ATPase |
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