糖尿病合并冠心病的青壮年男性患者冠状动脉造影分析

目的：探讨糖尿病（DM）合并冠心病（CHD）的青壮年男性患者冠状动脉造影（CAG）特点。方法：回顾性分析2011年1月至2013年1月在北京顺义医院住院，经CAG确诊的233例青壮年CHD患者临床资料，按是否患糖尿病分为DM合并CHD组（71例）和单纯 CHD组（162例），比较两组的基线资料和 CAG结果。结果：与单纯CHD患者比较，DM合并CHD患者总胆固醇[TC，（4.11±0.26）mmol/L比（5.79±0.37）mmol/L]、低密度脂蛋白胆固醇[LDL-C，（2.31±0.32）mmol/L比（3.91±0.45）mmol/L]、甘油三酯[TG，（1.60±0.25） mmol/L比（3.28±0.56）mmol/L]水平显著升高（P 均＜0.01）；CAG 显示的冠状动脉多支病变（15.4％比35.2％）、节段性病变（13.6％比35.2％）、弥漫性病变（31.5％比57.7％）比例显著增加，侧枝循环比例（50.6％比29.6％）显著减少，P均＜0.01。结论：冠心病合并糖尿病的青壮年男性患者冠状动脉病变以多支病变为主，弥漫性病变多，侧枝支循环建立不良。

Coronary angiographic data analysis in young male patients with type 2 diabetes mellitus complicated ;coronary heart disease

Objective：To explore the coronary angiographic （CAG）characteristics of young male patients With type 2 diabetes mellitus （T2DM）and coronary heart disease （CHD）.Methods：Clinical data of 233 young male CHD inpa-tients,Who Were confirmed by CAG and admitted in Beijing Shunyi Hospital from Jan 2011 to Jan 2013,Were retro-spectively analyzed.According to suffering from T2DM or not,they Were divided into T2DM ＋ CHD group （n=71）and pure CHD group （n=162）,baseline data and CAG results Were compared betWeen tWo groups.Results：Compared With pure CHD patients,there Were significant rise in levels of total cholesterol [TC,（4.11 ±0.26） mmol/L vs.（5.79±.37）mmol/L],loW density lipoprotein cholesterol [LDL-C,（2.31±.32）mmol/L vs.（3.91 ±.45）mmol/L],triglyceride [TG,（1.60±.25）mmol/L vs.（3.28±0.56）mmol/L],P〈0.01 all;CAG indi-cated that there Were significant increase in percentages of multi-vessel coronary disease （15.4% vs.35.2%）,seg-mental lesion （13.6% vs.35.2%）and diffused lesion （31.5% vs.57.7%）,and significant reduction in percentage of collateral circulation （50.6% vs.29.6%）in T2DM ＋ CHD patients,P〈0.01 all.Conclusion：There are more multi-vessel lesions,diffused lesion and less coronary collateral circulation in young male patients With type 2 diabe-tes mellitus complicated coronary heart disease.