陆眠宁复合麻醉巴马小型猪超声心动图检查分析

目的观察陆眠宁复合麻醉对小型猪的全身麻醉效果,强调全身麻醉的安全保障意识。采用超声心动图研究正常小型猪心脏的主要功能和结构,为后续比较医学研究做准备。方法 43头巴马小型猪,耳后颈部肌肉注射5 m L混合液:陆眠宁,硫酸阿托品,氟哌利多各1支,全麻后进行超声心动图检查。观察麻醉显效时间、麻醉维持时间、总检查时间、苏醒时间及其他麻醉相关情况。简介气管插管术。结果麻醉诱导期为(18±3)min,麻醉期(40±5)min,苏醒期(60±10)min。左房直径LAD(2.54±0.20)cm,左室舒张末直径LVDd(3.41±0.25)cm,左室收缩末直径LVDs(2.28±0.23)cm,室间隔厚度IVSTd(0.60±0.07)cm,左室后壁厚度LVPWTd(0.59±0.07)cm,主动脉宽度Ao D(1.77±0.18)cm,左室舒张末容积EDV(48.59±8.31)m L,左室收缩末容积ESV(18.28±4.46)m L,每搏输出量SV(39.30±5.16)m L,左室射血分数EF(62.76±5.01)%。结论陆眠宁与氟哌利多、硫酸阿托品复合麻醉,用于小型猪的心动图检查,是一种简便快速、安全有效的麻醉方法。本研究获得了正常小型猪心脏主要功能和结构的资料,为科研和兽医临床提供参考。

Echocardiography analysis of bama minipigs anesthesia by xylazine hydrochloride

Objective To explore effect of Xylazine hydrochloride on Bama minipigs under general anesthesia. To emphasize safety consciousness of general anesthesia. To research cardiac main function and structure of normal Bama minipigs in preparation for the subsequent comparative medicine research. Methods 43 Bama minipigs,inject in post aurem muscles of neck with 5 mL of mixed drug conclude Xylazine hydrochloride (2 mL), Atropine Sulfate(1 mL) and Droperidol(2 mL) on each one. Echocardiography after general anesthesia.Observe induction and recovery time of anesthesia, anesthesia maintaining time, total check time and the others. Introduce the method of simple endotracheal intubation.Results Anesthesia, induction period (18±3)min, maintaining period (40±5)min, recovery period (60±10)min. Echocardiography, LAD (2.54±0.20) cm, LVDd (3.41±0.25) cm, LVDs (2.28±0.23) cm, IVSTd (0.60±0.07) cm, LVPWTd (0.59±0.07) cm, AoD (1.77±0.18) cm, EDV (48.59±8.31) cm, ESV (18.28±4.46) mL, SV (39.30±5.16) mL, LVEF (62.76±5.01)%. Conclusions Intramuscular injection of xylazine hydrochloride with droperidol and atropine sulfate on bama minipigs for general anesthesia is a highly conserved specie in cardiovascular system and safe. We obtained some information of cardiac main function and structure of normal Bama minipigs which could provide reference for scientific research and veterinarian clinic.