| 预防全身麻醉诱导期间芬太尼所致咳嗽反应的临床研究 |
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| 引用本文： | 夏登云. 预防全身麻醉诱导期间芬太尼所致咳嗽反应的临床研究[J]. 河北医药, 2009, 31(21) |
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| 作者姓名： | 夏登云 |
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| 作者单位： | 河北北方学院附属第一医院麻醉科,河北省张家口市,075000 |
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| 摘 要： | 目的探讨静脉预先注射小剂量氯胺酮对全身麻醉诱导期间芬太尼所致咳嗽反应的预防作用。方法拟在全身麻醉下行择期手术患者40例,年龄18～65岁,体重40～80kg,美国麻醉学会(ASA)分级Ⅰ～Ⅱ级。患者随机分为2组,氯胺酮组(n=20)静脉注射氯胺酮0.15mg/kg,对照组(n=20)静脉注入等体积的0.9%氯化钠溶液;均于10s注射完毕,1min后,2组均静脉注射芬太尼3～5μg/kg,5s注射完毕。记录患者麻醉前和静脉注射芬太尼1min时(麻醉后)的咳嗽次数及其严重程度、收缩压、舒张压、心率。结果2组麻醉后收缩压、舒张压和心率间差异无统计学意义(P>0.05)。氯胺酮组咳嗽发生率低于对照组(P<0.05),出现咳嗽的时间晚于对照组(P<0.05),而咳嗽强度间差异无统计学意义(P>0.05)。结论静脉预先注射小剂量氯胺酮(0.15mg/kg)可有效降低麻醉诱导期间芬太尼所致咳嗽的发生率。
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| 关 键 词： | 氯胺酮 芬太尼 咳嗽 |
The clinical study of the preventive effect of intravenous injection of low-dose ketamine on cough reaction caused by fentanyl during the induction of general anesthesia |
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| XIA Dengyun. The clinical study of the preventive effect of intravenous injection of low-dose ketamine on cough reaction caused by fentanyl during the induction of general anesthesia[J]. Hebei Medical Journal, 2009, 31(21) |
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| Authors: | XIA Dengyun |
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| Affiliation: | XIA Dengyun.Department of Anesthesiology; The First Affiliated Hospital of Hebei North University; Hebei; Zhangjiakou 075000; China; |
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| Abstract: | Objective To investigate the preventive effect of intravenous injection of low-dose ketamine on cough reaction caused by fentanyl during the induction of general anesthesia.Methods 40 patients who were scheduled for surgery under general anesthesia,ASA grade Ⅰ~Ⅱ,aged 18 to 65 years and weighed 40 to 80kg,were randomly divided into two groups.The 20 patients in ketamine group were given ketamine 0.15mg/kg,however,the other 20 patients in control group were given equal volume of normal saline,which was finish... |
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| Keywords: | ketamine fentanyl cough |
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