| 仙鹤草煎剂对HL-60细胞的体外诱导凋亡作用 |
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| 引用本文： | 高凯民,周玲,陈金英,李凤琴,张玲.仙鹤草煎剂对HL-60细胞的体外诱导凋亡作用[J].中药材,2000,23(9):561-562. |
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| 作者姓名： | 高凯民 周玲 陈金英 李凤琴 张玲 |
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| 作者单位： | 1. 解放军济南医学高等专科学校,济南,250022
2. 山东省医学科学院,济南,250062 |
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| 摘 要： | 本研究采用ＭＴＴ法，细胞形态学观察和流式细胞术检测了仙鹤草煎剂对人白血病细胞系ＨＬ－６０在体外的作用。结果表明，仙鹤草煎剂对ＨＬ－６０细胞有生长抑制作用；用仙鹤草煎剂处理后的ＨＬ－６０细胞呈现出典型的凋亡形态特征；用流式细胞仪测定细胞周期，可见明显的凋亡峰。
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| 关 键 词： | 仙鹤草煎剂 HL－60细胞 细胞凋亡 白血病 |
| 修稿时间： | 2000年3月20日 |
Experimental Study on Decoctum Agrimonia pilosa Ledeb-induced Apoptosis in HL-60 Cells in Vitro |
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| Gao Kaimin,Zhou Ling,Chen Jinying,Li Fengqin,Zhang Ling.Experimental Study on Decoctum Agrimonia pilosa Ledeb-induced Apoptosis in HL-60 Cells in Vitro[J].Jorunal of Chinese Medicinal Materials,2000,23(9):561-562. |
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| Authors: | Gao Kaimin Zhou Ling Chen Jinying Li Fengqin Zhang Ling |
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| Institution: | PLA Jinan Junior College of Medicine, Jinan 250022. |
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| Abstract: | In this study, MTT assay, cell morphology and flow cytometry were used to explore Agrimonia pilosa Ledeb on HL-60 cells in vitro. The data suggested that Agrimonia pilosa Ledeb had the effects of growth inhibition in HL-60 cells. Aftert treated with decoctum Agrimonia pilosa Ledeb, cells underwent apoptosis with typical morphological feature.DNA histograms by flow cyto-metric analysis displayed distinct apoptotic peak. |
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| Keywords: | Agrimonia pilosa Ledeb Cell apoptosis |
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