| NES1基因在结肠癌细胞中表达及意义 |
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| 引用本文： | 饶雪峰,刘伟中,吴鹤立,赵辉,肖冬生. NES1基因在结肠癌细胞中表达及意义[J]. 江西医药, 2014, 0(10): 994-995 |
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| 作者姓名： | 饶雪峰 刘伟中 吴鹤立 赵辉 肖冬生 |
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| 作者单位： | 1. 江西省人民医院普外科,南昌,330006
2. 江西省共青城人民医院普外科,共青城,332000 |
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| 摘 要： | 目的：探讨NES1基因在结肠癌细胞中表达及意义。方法用RT-PCR方法检测NES1mRNA在正常结肠细胞、结肠癌细胞株HT29、HCT116表达情况。结果 NES1在结肠癌细胞株中表达较正常结肠黏膜细胞明显增高。结论 NES1基因在结肠癌的发生发展中起重要作用，这为选用NES1作为结肠癌治疗靶点提供了实验依据及理论基础。
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| 关 键 词： | NES1基因 结肠癌细胞 NES1 |
The expression and significance of NES1 in colon carcinoma cells |
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| Affiliation: | RA O Xuefeng,LIU Weizhong, WU Heli,et al. (Department of General Surgery, Jiangxi Provincial Hospital, Nanchang, 330006, China.) |
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| Abstract: | Objective To investigate the expression of NES1 in colon carcinoma cells and its significance. Methods The ex-pression of NES1mRNA in clon carcinoma cells and human colon cell was detected by RT-PCR technique. Results The expres-sion of NES1mRNA in colon carcinoma cell lines HT29 and HCT116 was significantly higher （P〈0.05）. Conclusion NES1 may play an important role of occurrence and development of colon carcinoma. |
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| Keywords: | NES1 RT-PCR colon carcinoma cells |
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