综合护理干预对肺癌化疗患者生存质量的影响

目的 探讨健康教育及综合护理干预对肺癌化疗患者生存质量的影响.方法 2010年2月至2013年2月,选取在我院住院化疗的100例肺癌患者,按照随机数字法分为干预组及对照组,每组各50例,对照组患者在化疗过程中仅给予常规抗癌药物治疗及常规基础护理,干预组在常规化疗及护理的基础上对患者进行健康教育,实施综合护理干预.于入组当时及研究结束时分别采用Zung焦虑量表（SAS）、抑郁量表评分（SDS）、生活质量核心问卷（QLQ-C30）对患者的生活质量进行评价,分析综合护理干预对肺癌化疗患者生存质量的影响.治疗前后采用配对样本t检验,组间比较采用单因素方差分析,以P＜0.05差异有统计学意义.结果 两组患者入组时的年龄、性别、病程、SAS、SDS评分、QLQ-C30评分差异均无统计学意义,一般资料具有可比性（均P＞0.05）.干预后对照组SAS评分及SDS评分分别为（58.8±7.6）分、（49.5±10.1）分,干预组SAS评分及SDS评分分别为（46.5±7.8）分、（37.4±9.2）分,与对照组相比明显降低,差异有统计学意义（t=5.347、6.215,P＜0.05）.干预后对照组生活质量各项评分：一般情况、体力评分、情感情分、认知评分、社会角色评分、功能评分分别为（47.3±23.0）分、（54.9±26.6）分、（60.4±19.1）分、（66.2±25.8）分、（54.1±26.2）分、（49.4±21.5）分,干预组分别为（57.2±18.3）分、（63.0±25.9）分、（67.3±23.3）分、（75.4±28.2）分、（67.7±24.8）分、（58.5±22.3）分,与对照组相比明显提高,差异均有统计学意义（t=5.725、6.144、5.021、5.702、7.137、6.357,均P＜0.05）.结论 对肺癌患者进行健康教育及综合护理干预可减少患者的焦虑及抑郁症状,全面提高患者的生活质量.

Effect of combination nursing intervention on quality of life in cancer patients undergoing chemotherapy

Objective To explore the effect of health education and comprehensive nursing intervention on quality of patients with lung cancer. Methods One hundred lung cancer patients who were treated with chemotherapy from February 2010 to February 2013 in our hospital were selected and assigned to the intervention group （n=50） and the control group （n=50）. The participants in the control group received conventional anti-cancer drug and routine primary care, however those of the intervention group additionally obtained health education and comprehensive nursing intervention. The Zung Anxiety Scale （SAS）, Depression Rating Scale （SDS） and the core quality of life questionnaire （QLQ-C30） were used to evaluate the quality of life of the patients. Paired samples t test and ANOVA were used for data analysis. Results Differences of age, gender, disease duration, SAS, SDS score and EORTC QLQ-c30 score were not statistically significant between the two groups （all P〉0.05）. After the intervention, SAS and SDS scores of the control subjects were 58.8±7.6 and 49.5±10.1 respectively, and SAS and SDS scores of the intervention group were 46.5±7.8 and 37.4±9.2 respectively （t velues were 5.347 and 6.215, respectively; both P〈O.05）. Quality of life scores in the intervention group were as followed： general condition 57.2± 18.3, physical fitness 63.0±25.9, mutual affection 67.3±23.3, cognitive score 75.4±28.2, social role 67.7±24.8 and function scores 58.5±22.3. Quality of life scores in the control group were as followed： general condition 47.3±23.0, physical fitness 54.9±26.6, mutual affection 60.4± 19.1, cognitive score 66.2±25.8, social role 54.1±26.2 and function scores 49.4±21.5 （t values were 5.725, 6.144, 5.021, 5.702, 7.137 and 6.357, respectively; all P〈0.05）. Conclusion Health education and comprehensive nursing intervention for lung cancer patients may reduce their anxiety and depression symptoms and improve the quality of life.