| 甜茶素提取物对STZ致高血糖大鼠的降血糖作用研究 |
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| 引用本文： | 田翠平,瞿伟菁,孙斌,李明娟,汪虹,黄晓青. 甜茶素提取物对STZ致高血糖大鼠的降血糖作用研究[J]. 营养学报, 2003, 25(1): 29-33 |
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| 作者姓名： | 田翠平 瞿伟菁 孙斌 李明娟 汪虹 黄晓青 |
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| 作者单位： | 华东师范大学生命科学学院,上海,200062 |
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| 基金项目： | 上海市科技发展基金资助项目 ( N o. 0 0 3912 0 74) |
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| 摘 要： | 目的 : 研究甜茶素提取物对 STZ致高血糖大鼠的降血糖效果及其降糖机制。方法 : 腹腔注射 STZ制备糖尿病大鼠模型 ,取成型的大鼠随机分阳性对照组、甜茶素提取物组和降糖灵组。同时设一正常组。灌胃 3 w后 ,测血糖、果糖胺、胰岛素和 SOD等指标。结果 : 甜茶素提取物能极显著地降低 STZ致高血糖大鼠血糖 ,增强其抗氧化能力 ,同时能刺激胰岛素的分泌。结论 : 甜茶素提取物通过刺激胰岛素的分泌来降低血糖
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| 关 键 词： | 甜茶素 链脲佐菌素 高血糖大鼠 胰岛素 |
| 文章编号： | 0512-7955(2003)01-0029-05 |
| 修稿时间： | 2002-09-23 |
EFFECT OF RUBUSOSIDE EXTRACTS ON HYPERGLYCEMIC RATS INDUCED BY STREPTOZOTOCIN |
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| TIAN Cui ping,QU Wei jing,SUN Bin,LI Ming juan,WANG Hong,HUNG Xiao qing. EFFECT OF RUBUSOSIDE EXTRACTS ON HYPERGLYCEMIC RATS INDUCED BY STREPTOZOTOCIN[J]. Acta Nutrimenta Sinica, 2003, 25(1): 29-33 |
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| Authors: | TIAN Cui ping QU Wei jing SUN Bin LI Ming juan WANG Hong HUNG Xiao qing |
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| Abstract: | Objective: To study the anti hyperglycemic effect of rubusoside on diabetic rats induced by streptozotocin (STZ)and its mechanism . Methods: The STZ induced diabetic rats were dived into three groups and were given (ig.) saline, rubusoside and Phenformin respectively once a day. After three weeks, the levels of serum glucose, fructosamine, insulin,SOD were assayed. Results: Rubusoside could reduce the level of serum glucose significantly, enhance the ability of anti oxidation and stimulate the secretion of insulin in STZ induced diabetic rats. Conclusion: The action of rubusoside on secretion of insulin can be explained for the anti hyperglycemic effect. |
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| Keywords: | rubusoside extraction streptozotocin hyperglycemic rat Insulin |
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