25例腹内型侵袭性纤维瘤病临床分析

[目的]探讨腹内型侵袭性纤维瘤病的临床特点、治疗方法和预后。[方法]回顾性分析1999年1月至2013年3月收治的25例腹内型侵袭性纤维瘤病患者的临床资料,生存分析采用Kaplan-Meier法。[结果]5、10年生存率分别为94.4%和70.7%,无复发生存率分别为68.7%和58.9%。肿瘤最大径≥10cm（χ2=5.074,P=0.024）和接受姑息性手术（χ2=6.131,P=0.013）的患者预后较差。[结论]腹内型侵袭性纤维瘤病术前难以确诊,首选手术治疗,肿瘤大小和能否根治性切除是其预后影响因素。

Clinical Analysis of 25 Cases with Intra-abdominal Aggressive Fibromatosis

[Purpose] To investigate the clinical characteristics,treatments and prognostic risk factors of patients with intra-abdominal aggressive fibromatosis.[Methods] The clinical data of 25 cases with intra-abdominal aggressive fibromatosis admitted from January 1999 to March 2013 were retrospectively analyzed. The survival functions were analyzed by Kaplan-Meier. [Results] The 5-year and 10-year survival was 94.4% and 70.7%,respectively. The 5-year and 10-year recurrence-free survival rate was 68.7% and 58.9%,respectively. Prognosis of patients with tumor size ≥10cm（χ2= 5.074,P=0.024）and undergoing palliative operation（χ2=6.131,P=0.013） was worse than that with size10cm and undergoing radical operation. [Conclusion] It is difficult to diagnose the intra-abdominal aggressive fibromatosis before operation. Surgery is the first choice of treatment. Tumor size and weather radical surgery being performed are risk factors of the prognosis of intra-abdominal aggressive fibromatosis.