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Increased whole body hydroxyproline production as assessed by a new stable isotope technique is associated with hip and spine bone mineral loss in cystic fibrosis
Affiliation:1. 2nd Department of Internal Medicine, Osaka Medical College, Osaka, Japan;2. Department of Chemistry, Osaka Medical College, Osaka, Japan;1. Department of Geography, Johannes Gutenberg University, Becherweg 21, 55099 Mainz, Germany;2. Department of Physical Geography and Quaternary Geology, Stockholm University, 10691 Stockholm, Sweden;3. German Centre for Geosciences-GFZ, Section 5.2 Climate Dynamics and Landscape Evolution, Potsdam, Germany;4. Swiss Federal Research Institute for Forest Snow and Landscape (WSL), 8903 Birmensdorf Switzerland;5. Paul Scherrer Institut, Villigen PSI, Switzerland;1. Department of Environmental Science and Technology, School of Human Settlements and Civil Engineering, Xi''an Jiaotong University, Xi''an 710049, China;2. State Key Laboratory of Loess and Quaternary Geology, Institute of Earth Environment, Chinese Academy of Sciences, Xi''an 710061, China;3. Key Laboratory of Disaster Monitoring and Mechanism Simulating of Shaanxi Province, Baoji University of Arts and Sciences, Baoji 721013, China;4. The Eleventh Middle School of Dalian Development Zone, Dalian 116635, China;5. Department of Geography, Xingtai University, Xingtai 054001, China;6. Honghuaerji Forestry Bureau of Inner Mongolia, Honghuaerji 021112, China
Abstract:
Keywords:Cystic fibrosis  Whole body hydroxyproline production  Collagen breakdown  Bone mineral density  Stable isotope  Lung function  BA"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0045"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  bone area  BMAD"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0055"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  bone mineral apparent density  BMD"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0065"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  bone mineral density  BMI"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0075"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  body mass index  BMIp"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0085"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  body mass index percentile  CRP"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0095"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  C-reactive protein  CF"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0105"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  cystic fibrosis  CFF"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0115"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  cystic fibrosis foundation  DXA"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0125"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  dual-energy X-ray absorptiometry  forced expiratory volume in 1 s  FFM"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0145"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  fat-free mass  FFMI"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0155"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  fat-free mass index  FM"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0165"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  fat mass  FMI"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0175"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  fat mass index  FVC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0185"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  forced vital capacity  OH-PRO"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0195"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  hydroxyproline
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