Treatment of severe cholestatic hepatitis by integrating traditional Chinese and Western medicines

Objective: To study the curative effect of Chinese medicines in treating severe cholestatic hepatitis (SCH).Methods: Three hundred and fifty patients of SCH with total bilirubin level 171 μmol/L were treated with Chinese medicines. Those with Blood Stasis Syndrome were treated with the recipe mainly consisting of Radix Paeoniae Rubra, and those accompanied by blood Heat, fluid retention in the epigastric region, dampness disseminated in Sanjiao ( ) or Yang deficiency of both Spleen and Kidney were treated with recipe modified according to the symptoms and signs.Results: The treatment was markedly effective in 288 cases and effective in 26 cases, the total effective rate being 89.7%.Conclusion: It is difficult to treat severe cholestatic hepatitis, es pecially the chronic cholestatic good effect of Chinese herbal medicine in eliminating jaundice. The above research work won the second price for advanced science and technology awarded by the Ministry of Health of the General Logistic Department