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胃舒通颗粒对大鼠慢性胃炎胃液影响的实验研究
引用本文:宫照东. 胃舒通颗粒对大鼠慢性胃炎胃液影响的实验研究[J]. 辽宁中医学院学报, 2010, 0(8): 124-125
作者姓名:宫照东
作者单位:辽宁中医药大学,辽宁沈阳110032
摘    要:目的:观察胃舒通颗粒对大鼠慢性胃炎的作用。方法:采用去氧胆酸钠加乙醇灌服大鼠制作慢性胃炎模型。测定给药后大鼠胃液分泌量、胃酸PH、胃液总酸度值、胃蛋白酶活性的变化。结果:与模型组相比,使胃液pH值降低,胃酸分泌量增多,使胃蛋白酶的活性降低,胃黏膜的损伤减轻。结论:胃舒通颗粒对慢性胃炎大鼠胃液有调节作用从而起到保护胃黏膜的作用。

关 键 词:胃舒通颗粒  慢性胃炎  胃蛋白酶活力

Experiment and Study of WeiShuTong Particles on Mice Chronic Gastritis and Gastric Juice
GONG Zhao-dong. Experiment and Study of WeiShuTong Particles on Mice Chronic Gastritis and Gastric Juice[J]. Journal of Liaoning College of Traditional Chinese Medicine, 2010, 0(8): 124-125
Authors:GONG Zhao-dong
Affiliation:GONG Zhao-dong (Liaoning University of Traditional Chinese Medicine,Shenyang 110032, Liaoning,China)
Abstract:Objective: Observe the function of WeiShuTong particles to cure mice chronic gastritis. Methods: Irrigate the mice chronic gastritis model by using deoxycholic acid sodium plus ethanol. Test the gastric acid secretion, PH, total gastric acidity value, total pepsin activity of change after irrigation. Results: Compared with model group, WeiShuTong particles reduce the gastric acid secretion, pH value, lower the activity of pepsin, and lighten the gastric mucosal injury. Conclusion: WeiShuTong particles have adjustment function toward the gastric acidity of the chronic gastritis mice and also protect the gastric mucosa.
Keywords:WeiShuTong particles  chronic gastritis  active pepsin
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