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正交实验优选律复康胶囊脂溶性部分提取工艺
引用本文:陈舒茵,申洪超,黎瑞汝,韩丽华,王振涛,梁生旺.正交实验优选律复康胶囊脂溶性部分提取工艺[J].辽宁中医学院学报,2010(6):77-79.
作者姓名:陈舒茵  申洪超  黎瑞汝  韩丽华  王振涛  梁生旺
作者单位:[1]广东药学院中药学院,广东广州510006 [2]河南省中医院,河南郑州450003
基金项目:河南省科技创新人才计划项目(0621002700)
摘    要:目的:优选律复康胶囊醇提部分的最佳工艺。方法:应用正交试验设计,采用高效液相色谱法测定人参皂苷Rg1、Re的含量,浸出物测定法测定正丁醇萃取物出膏率。结果:最佳提取工艺为:加8倍量的70%乙醇,煎煮2次,每次1h。结论:该提取方法合理、可行,工艺稳定可靠,适用于工业化大生产。

关 键 词:律复康胶囊  提取工艺  高效液相色谱法  人参皂苷Rg1  人参皂苷Re  正丁醇提取物

Optimization of Extraction Process for Fatty Contents from Lvfukang Capsules by Orthogonal Test
ChEN Shu-yin,ShEN Hong-chao,LI Rui-ru,HAN Li-hua,WANG Zhen-tao,LIANG Sheng-wang.Optimization of Extraction Process for Fatty Contents from Lvfukang Capsules by Orthogonal Test[J].Journal of Liaoning College of Traditional Chinese Medicine,2010(6):77-79.
Authors:ChEN Shu-yin  ShEN Hong-chao  LI Rui-ru  HAN Li-hua  WANG Zhen-tao  LIANG Sheng-wang
Institution:1.Guangdong Pharmaceutical University,Guangzhou 510006,Guangdong,China ;2.Henan Hospital of Traditional Chinese Medicine,Zhengzhou 450003,Henan,China)
Abstract:Objective:To study the best extracting technology for aqueous substance of Lvfukang Capsules.Method :Orthogonal optimization was used in the experiment and the content of panaxsaponin Rg1 panaxsaponin Re was determined by HPLC,the rate of n-butanol matter was determined by assay of extractum.Result :The ideal extraction process is :the medicine is extracted for two times,with 8 times of 70% alcohol,boiled for 1 hour.Conclusion :The best extracting technology is rational and feasible,it is labile and applicable to the industry manufacture.
Keywords:Lvfukang Capsules  extracting technology  HPLC  panaxsaponin Rg1  panaxsaponin Re  n-butanol matter
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