| 阿托品对氢化可的松快速作用的影响 |
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| 引用本文： | 易必达,马蓓.阿托品对氢化可的松快速作用的影响[J].贵阳医学院学报,1999,24(1):1-3. |
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| 作者姓名： | 易必达 马蓓 |
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| 作者单位： | [1]贵阳医学院生理教研室 [2]第二军医在大学生理学教研室 |
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| 摘 要： | 在离体灌注的牛蛙交感神经节上，氢化可的松一方面通过Ｎ受体介导，快速抑制Ｂ细胞的快尖奋性突触后电位，引起Ｂ细胞突触 传递的阻断。氢化可的松的又同时通过Ｍ受体介导，快速增强Ｂ细胞的慢兴奋性突触 后电位，提高Ｂ细胞的兴奋性，使重复放电增加。
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| 关 键 词： | 氢化可的松 阿托品 交感神经节 突触传递 牛蛙 |
Effects of Atropine on Rapid Effects of Hydrocortisone 21 Hemisuccinate |
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| Yi Bida,et al..Effects of Atropine on Rapid Effects of Hydrocortisone 21 Hemisuccinate[J].Journal of Guiyang Medical College,1999,24(1):1-3. |
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| Authors: | Yi Bida |
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| Institution: | Yi Bida,et al. Department of Physiology,Guiyang Medical College |
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| Abstract: | Effects of atropine on rapid modulation of synaptic responses of B neurons by hydrocortisone 21-hemisuccinate(F suc) were investigated. The results were as follows: F suc inhibited fast excitatory postsynaptic potential (fEPSP)by modulating N receptor and blocked the synaptic transmission of B neurons in the bullfrog sympathetic ganglia in vitro. Meanwhile, F suc also potentiated slow excitatory postsynaptic potential (sEPSP)by modulating M receptor and raised excitability of B neurons. It may promote repetitive discharges on B neurons. Atropine blocked M receptor and depressed sEPSP. Therefore atropine may potentiate rapid inhibitory effects on synaptic transmission of B neurons by applying F suc. |
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| Keywords: | hydrocortisone atropine sympathetic ganglia synaptic transmission rana catesbeiana |
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