脑梗死早期智能障碍与脑影像学改变关系分析

目的　探讨脑梗死患者智能障碍与脑影像学及其它因素之间的关系。方法　应用韦氏智力量表对经CT证实的 16 6例脑梗死患者进行神经心理学检查。对比分析其智能障碍的发生与性别、年龄、文化程度、脑梗死灶的部位、体积、是否伴发皮层萎缩或皮层下变性影像学结果的关系。结果　92例出现智能障碍 ,其中轻度 46例 ,中度 2 1例 ,重度 2 5例。智能障碍与其梗死体积呈明显正相关 ,与各皮层及皮层下萎缩因子呈明显负相关 ,与文化程度呈明显负相关。结论　智能障碍的发生与梗死体积 ,慢性脑循环障碍所致皮层及皮层下病理改变 ,以及文化程度的差异等多种因素有

Analysis on the relationship between intellectual impairment and brain photographic changs in early period of cerebral infarct

Objective In order to explore the correlation between intellectual impairment and cranical computect tomographic changes in cerebral infarct patients. Methods 166 cases of cerebral infarct patients identified by CT findings were studied with the neuropsychological tests. To analyze the correlation among the occurrence of intellectual impairment and sex, age, education level, the location and extent of focal lesions as the pressense of cerebral atrophy or subcortical degeneration in 92 cerebral infarct dementia index cases and 74 cerebral infarct without dementia index cases. Results 55 4% of them were shown to have intelligence impirment, including light degree 27 7%, moderate 12 7%, severe 15 1%. The intellectual impairmet was positively relative to extent of focal lesion, but negatively relative to the cerebral atrophy factor, subcortical degeneration factor and education levels.Conclusions It was suggeste that a single explanation for vascular dementia is not adequate. Rather, multiple factors including extent of focal lesions, pathologic changes of cerebrol and subcortical with chronic brain circulation disorder and low educational level, may independently contribute to intellectual impairment.