婴幼儿体内微量和常量元素水平与发育迟缓的相关性研究

目的：检测发育迟缓患儿体内铜、锌、铁、钙、镁、碘、铅和镉8种元素含量的变化,并探讨其与发育迟缓的关系.方法：随机选择150例发育迟缓患儿和150例正常对照婴幼儿进行问卷调查及发育商检查,同时采用原子吸收光谱法检测血锌、铁、铜、钙、镁、铅和镉,用砷铈催化法检测尿碘,并对检测的8种元素含量作比较分析.结果：①发育迟缓组锌、铁和碘水平低于正常对照组,两组间差异有统计学意义（P＜0.01）;而铜、钙、镁、铅和镉两组间差异无统计学意义（P＞0.01）.②单因素分析结果表明：锌、铁和碘与发育商显著相关（P＜0.05）.③多因素分析结果表明：影响婴幼儿发育商的主要因素是铁和碘（P＜0.05）.结论：锌、铁、碘缺乏是婴幼儿智力发展的危险因素,加强营养预防缺乏是防治婴幼儿发育迟缓发生的有效途径.

Detection and Analysis of Trace and Major Eiements in Infants with Global Developmental

Objective： To detect the contents chang of zinc, iron, copper, calcium, magnesium, lead and cadmium in infants with global developmental Delay, and analyze the relationship of global developmental Delay and eight elements in infants. Methods： Ran - dom sampling of infants aged 〈 3 was performed. Meanwhile, questionnaire and mental - te st was carried out. blood zinc, iron, copper, calcium, magnesium, lead and cadmium were de - tected by atomic absorption spectrophotometry and urine iodine was detected by arsenic ce - ri- um catalyst. Results： ①zinc,iron and iodine in the GDD group are significantly lo - wet than those in the control group（P〈 0.01）. there are no significant differences between the twogroup of copper, calcium, magnesium, lead and cadmium（P 〉 0.05）.②simple regression results showed; zinc、iron and iodine were positively correlated with DQ（P 〈0.05）. ③multiple regression results suggested that DQ was primarily related with iron and iodine. Conclusion： The deficiency of zinc, iron and cadmium is danger factors to GDD. Early su- pplyment is an effetive meatuer to prevent infants from GDD.