痤疮患者与健康者面部生理指标的测定

目的通过对寻常性痤疮患者及健康者面部生理指标的测定比较，探讨其特点，为指导痤疮治疗提供参考。方法选取受试者80例，其中实验组为痤疮患者40例，对照组为体检健康者40例。运用无创皮肤生理功能测试仪，测量受试者额部、眼角、面颊、U区的皮肤油脂、弹性、水分、经皮肤丢失水价量（TEWL）、皮肤红色素指数等数据。结果实验组痤疮患者额部、面颊部油脂明显高于对照组，实验组面颊、U区水分低于对照组，差异均有统计学意义（P〈0．05）。实验组面部的额区、面颊TEwL高于对照组，差异均有统计学意义（P〈0．05）。实验组面部的额区、面颊、U区的皮肤红色素指数高于对照组，差异均有统计学意义（P〈0．05）。而实验组面部各部位弹性与对照组比较，差异无统计学意义（P〉0．05）。结论痤疮患者皮损区油脂分泌过多，皮肤屏障功能降低。

Physiometry of facial skin in patients with acne and healthy individuals

Objective To approch ache characteristics and to facilitate its treatment by compa- ring the skin physiology function of patients with acne and healthy individuals. Methods Forty pa- tients with acne and 40 healthy controls were included into this study. Cutometer, Sebumeter, Corne- ometer, Tewameter, and Mexameter were used, respectively, to measure the skin elasticity, sebum, water, trans-epidermis water loss and red pigment index in the following facial areas： forehead, lateral canthus, right and left cheek, right and left U-zone. Results A significant increase was observed in the level of sebum in the forehead, right and left cheek of patients as compared with controls （P〈0.05）. A significant decrease was observed in the level of water in the right and left cheek and U-zone of patients compared with controls （P〈0. 05）. A significant decrease was observed in the level of trans-epidermis water loss in the right and left cheek and forehead of patients compared with controls （P〈0.05）. A significant increase was observed in the level of red pigment index in the right and left cheek, forehead, right and left U-zone of patients compared with controls （P〈0.05）. However, the level of skin elasticity was of no significant difference between the patients and controls （P〉0.05）. Conclusions Compared with the controls facial sebum secretion is increased with reduced skin barrier function in patients with acne.