应用OCT观察Lucentis治疗视网膜静脉阻塞性黄斑水肿的疗效

目的：观察玻璃体腔注射Lucentis治疗视网膜静脉阻塞继发黄斑水肿的疗效。方法：回顾性分析玻璃体腔注射Lucentis治疗视网膜静脉阻塞性黄斑水肿患者44例（44眼），定期随访6个月。观察治疗前及治疗后1d，2周，1、3、6个月时最佳矫正视力，OCT显示的黄斑中心凹厚度变化及并发症。结果：Lucen-tis玻璃体腔注射2周。1、3、6个月平均最佳矫正视力均提高，差异有统计学意义（P〈0．05）。随访中未见与注射及药物有关的眼部及全身不良反应。结论：Lucentis玻璃体腔注射治疗视网膜静脉阻塞引起的黄斑水肿安全有效，操作简单，必要时可重复注射治疗。

The Clinical Study on Intravitreous Injection of Lucentis For Macular Edema in Retinal Vein Occlusion by OCT

Objective： To observe the curative effect of intravitreal injection of Lucentis for treatment of retinal vein occlusion（RVO） with macular edema（ME）. Methods： This is a retrospective study on 44 cases （44 eyes） with macular edema induced by RVO. All of the patients received intravitreous injection of lucentis, andwere regular followed up for 6 months. To observe the BCVA, CMT and complications before injection and 1 day, 2 weeks, and 1,3, 6months after initial injection. Results：The mean BCVA was significantly improved at 2 weeks and 1, 3, 6 months after injection in comparison with before injection（p 〈 0.05）. No ocular or systemic adverse events were found after intravitreal injection of lucentis during the follow- up duration. Conclusion： In- travitreous injection of lucentis for ME in RVO is safe, effective and simole operation.