HPV检测在宫颈癌及癌前病变中诊断及随访的意义

宫颈癌是最常见的妇科恶性肿瘤之一,其发病率居女性恶性肿瘤第二位.近年来宫颈癌发生率呈上升趋势,由于子宫颈癌的发生、发展是由一个量变、渐变到突变的过程,经历癌前病变、早期浸润癌和浸润癌3个阶段,因此,早期诊断和治疗非常重要.目前子宫颈癌可经手术、放疗和化疗等综合治疗得到有效治疗,其5年生存率较高,但因其复发率仍较高,对子宫颈癌及癌前病变复发患者及时干预以提高其生活质量及延长生存期非常重要.研究者致力于寻找指标,如HPV检测,以应用于子宫颈癌及癌前病变的早期诊断、疗效观察、预后评估及预测复发.综述HPV检测在子宫颈癌及癌前期病变中的应用价值.

The Value Of HPV Testing With Cervical Cancer and Cervical Precancerous Lesions

Cervical cancer is one of the most common gynecologic malignancy and its incidence is in the second malignancy among the women . The incidence of cervical cancer is rising in recent years. Since the incidence and development of cervical cancer is a process of quantitative, gradient, to mutation. Cervical Cancer experienced three stages including precancerous lesions and early invasive and invasive, early diagnosis and treatment is very important. Currently cervical cancer can be treated effectively by surgery, radiotherapy and chemotherapy combined therapy, and the 5 - year survival rate is considerable. Because of cervical cancer recurrence rate is still high, it is important for the recurrence of cervical cancer and precancerous lesions patients that timely intervention in order to improve their quality of life and prolong survival. Researchers dedicated to finding indicators, such as HPV testing, which can be used in early diagnosis, treatment response monitoring, prognosis and recurrence prediction of cervical cancer and lesion precancerous. In this paper, HPV testing in the value of cervi cancer and lesion precancerous start review.