| 检测血清可溶性白细胞介素－2受体在恶性肿瘤诊断中的应用 |
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| 引用本文： | 吕先科,尹正, 许亚兰. 检测血清可溶性白细胞介素－2受体在恶性肿瘤诊断中的应用[J]. 中国医科大学学报, 1994, 0(3) |
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| 作者姓名： | 吕先科 尹正 许亚兰 |
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| 作者单位： | 中国医科大学第二临床学院免疫室，辽宁省肿瘤医院检验科 |
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| 摘 要： | 应用双抗夹心ＥＬＩＳＡ法检测１１１例各类恶性肿瘤患者血清中可溶性白细胞介素－２受体（ｓＩＬ－２Ｒ）水平。结果表明，恶性肿瘤患者ｓＩＬ－２Ｒ水平明显高于正常人（Ｐ＜０．０１），而肺癌、乳腺癌、肝癌、胃癌、膀胱癌、卵巢癌及宫颈癌之间无明显差异（Ｐ＞０．０５）。在４５例肺癌中，有转移者的ｓＩＬ－２Ｒ水平明显高于无转移者（Ｐ＜０．０１）。ｓＩＬ－２Ｒ对恶性肿瘤的诊断，治疗和预后的判断具有重要意义。
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| 关 键 词： | 恶性肿瘤；可溶性白细胞介素－2受体 |
The Determination of Serum Soluble Interleukin-2 Receptor for the Diagnosis of Carcinoma |
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| Lu Xianke,Yen zheng,Xu Yazheng. The Determination of Serum Soluble Interleukin-2 Receptor for the Diagnosis of Carcinoma[J]. Journal of China Medical University, 1994, 0(3) |
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| Authors: | Lu Xianke Yen zheng Xu Yazheng |
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| Affiliation: | Immunological Lab.The second Affiliated Hospital |
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| Abstract: | he serum soluble interleukin-2 receptor(sIL-2R)in 111 patients with various carcinomas was mea-sured by sandwith ELISA with double antibodies. The results showed that the level of sIL-2 in patientswith carcinoma was higher than that of controls(P<0.01 ),whereas no difference was found for thelevel of sIL-2R among patients with lung , breast,hepatic,gastric,bladder,ovarium, and cervical car-cinoma( P >0.05).Among 45 cases with lung cancer ,the level of sIL-2R in subjects with metastasiswas obviously higher than that of patients with cancer in situ( P <0.01).The results suggested thatsIL-2R was of important value for the diagnosis,treatment and prognosis of carcinoma. |
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| Keywords: | carcinoma sIL-2R |
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