| PET/CT在动物领域的研究进展 |
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| 引用本文： | 陈雪祺,王荣福.PET/CT在动物领域的研究进展[J].中国医学装备,2013(1):55-59. |
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| 作者姓名： | 陈雪祺 王荣福 |
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| 作者单位： | 北京大学第一医院核医学科 |
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| 基金项目： | 国家自然科学基金(30870729)“靶向肿瘤血管多肽显像与治疗实验研究”,国家自然科学基金(81071183)“核素靶向示踪肿瘤新生血管作用位点研究);国家重大科学仪器设备开发专项(2011YQ03011409)“基于多模态分子影像技术的新型肿瘤新生血管靶向显像剂及治疗药物的在体评价系统研究” |
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| 摘 要： | 目前PET/CT已作为我国最先进的分子影像技术之一,在临床和科研工作中具有举足轻重的地位,并经历了十余年平稳而快速的发展。小动物PET/CT虽然起步较晚,但在活体动物实验领域中已显示其灵敏度高、准确性好、检查便捷、成像清晰等优势,为临床研究奠定了坚实的基础。同时,由于专用小动物PET/CT使用成本较高,将临床PET/CT更好地用于小动物领域的研究工作已取得了较大的进步,且在肿瘤组织、心血管系统及运动系统等具体方向的实验研究中发挥了重要作用。
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| 关 键 词： | 正电子发射断层显像术 体层摄影术 X线计算机 分子影像 动物疾病模型 |
Advancement in researches of small animal PET/CT and its application in disease models |
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| CHEN Xue-qi, WANG Rong-fu.Advancement in researches of small animal PET/CT and its application in disease models[J].China Medical Equipment,2013(1):55-59. |
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| Authors: | CHEN Xue-qi WANG Rong-fu |
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| Institution: | Department of Nuclear Medicine, the First Clinical College of Beijing University, Beijing 100034, China. |
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| Abstract: | Over the past decades, great success has been achieved for PET/CT in China. PET/CT could be a useful molecular imaging modality in various phases of disease progression. Meanwhile, animal PET/CT could be used in preclinical studies and shows a high sensitivity and accuracy, making it a powerful tool in animal experiments. With the consideration of the high cost of dedicated small animal PET/CT, many scientists pay attention to the utility of clinical PET/CT for small animal research and they have made great progress in the study of tumor tissue, cardiovascular system and locomotor system. |
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| Keywords: | Positron-emission tomography Tomography X-ray computed Molecular imaging Animal disease model |
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