3．0T磁共振灌注加权成像在脑胶质瘤诊断中的价值

目的探讨3.0T磁共振灌注加权成像在脑胶质瘤术前分级及与脑单发转移瘤鉴别诊断中的价值。方法对经病理证实的脑胶质瘤患者（低级别15例,高级别17例）和单发转移瘤患者14例的MR灌注加权成像资料进行回顾性分析,测算肿瘤实质区与瘤周水肿区的相对脑血容量（rCBV）值,并进行统计学分析。结果 （1）在肿瘤实质区,低级别胶质瘤的rCBV值为（1.982±0.436）低于高级别胶质瘤rCBV值（5.574±1.124）,在瘤周水肿区,低级别胶质瘤的rCBV值为（0.796±0.215）低于高级别胶质瘤的rCBV值（1.497±0.192）,差异均有统计学意义（P〈0.05）;（2）在肿瘤实质区,单发转移瘤的rCBV值为（3.087±1.017）低于高级别胶质瘤的rCBV值（5.574±1.124）,在瘤周水肿区,单发转移瘤的rCBV值为（0.356±0.145）低于高级别胶质瘤的rCBV值（1.497±0.192）,差异均有统计学意义（P〈0.05）。结论灌注加权成像作为一种无创性的评价手段,可以提高脑胶质瘤术前分级的准确性,并在与单发转移瘤鉴别诊断方面有一定临床价值。

The value of 3.0 T MR perfusionweighted imaging in diagnosis of gliomas

Objective To evaluate the value of 3.0 T MR perfusionweighted imaging （PWI） in grading brain glio- mas and differential diagnosis of gliomas and solitary metastatic tumors. Methods Conventional MR imaging and PWI were performed in 15cases of lowgrade gliomas, 17cases of highgrade gliomas, and 14 cases of solitary metastatic tumors. All cases were pathologically proved after operation. The rCBV value in the tumor parenchyma area and the peritumoral edema area are calculated and statistically analyzed. Results （1） In the tumor parenchyma area, the rCBV value of lowgrade gliomas was （1. 982±0. 436） ,which was lower than （5. 574± 1. 124） of highgrade gliomas （P〈0. 05）. In the peritumoral edema area,the rCBV value of lowgrade gliomas was （0. 796±0. 215）,which was lower than （1. 497±0. 192） of highgrade gliomas （P〈0.05）. （2）In the tumor parenchyma area, the rCBV value of metastatic tumors was（3. 087±1. 017）,which was lower than （5. 574± 1. 124） of highgrade gliomas （P〈0.05）. In the peritu- moral edema area,the rCBV value of metastatic tumors was（0.356±0. 145） ,which was lower than （1. 497±0. 192） of highgrade gliomas （P〈0.05）. Conclusion PWI can be used in grading brain gliomas and differentiating gliomas from solitary metastatic tumors as a noninvasive means.