Association between Helicobacter. <Emphasis Type="Italic">pylori</Emphasis> and coronary artery disease |
| |
Authors: | Setareh Davoudi Abbas Salehi Omran Mohammad Ali Boroumand Nasrin Rahimian Soheil Saadat |
| |
Institution: | (1) Department of Clinical Microbiology, Kocaeli University, Kocaeli, Turkey;(2) Cardiology Department, Central Hospital, Izmir, Turkey;(3) Cardiology Department, Onsekiz Mart University, Canakkale, Turkey;(4) Department of Biochemistry, Kocaeli University, Kocaeli, Turkey |
| |
Abstract: | The high prevalence of both Helicobacter.pylori infection and coronary atherosclerosis in our country prompted us to assess the probable association between both conditions.
This cross-sectional study recruited 153 patients scheduled to undergo coronary artery angiography. Patients were divided
into two groups on the basis of coronary angiography results. Sixty-nine patients had coronary atherosclerosis and the 84
remaining patients were normal. Characteristics and pre-angiographic serum levels of triglyceride, low-density lipoprotein
cholesterol, high-density lipoprotein, and Helicobacter.pylori IgG antibody were assessed in the patients and compared between
the groups. Helicobacter.pylori infection occurred in 88 (57.51%) patients: 40 (58%) in the atherosclerotic group and 48 (57.1%) in the control group with
no significant differences (P=0.918). Our multivariable analysis revealed that Helicobacter.pylori infection was not an independent
predictive factor for coronary artery disease (P =0.915). Also, the prevalence of atherosclerosis risk factors with respect
to the seropositive and seronegative Helicobacter.pylori infection was assessed in the case group, which showed no significant difference. Furthermore, the prevalence of seropositive
Helicobacter.pylori infection in terms of the number of diseased coronary vessels was evaluated, this demonstrated no significant association
between the number of the diseased vessels and Helicobacter.pylori infection. This study demonstrated that Helicobacter.pylori infection was not an independent predictive factor of atherosclerosis. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|