| 76例药物性肝病的临床特点分析 |
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| 引用本文： | 毛靖伟,唐海英,王英德.76例药物性肝病的临床特点分析[J].胃肠病学和肝病学杂志,2011,20(2):153-155. |
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| 作者姓名： | 毛靖伟 唐海英 王英德 |
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| 作者单位： | 1. 大连医科大学附属第一医院,消化内科,辽宁,大连,116011
2. 大连医科大学附属第一医院,呼吸内科,辽宁,大连,116011 |
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| 摘 要： | 目的通过对药物性肝病的病因、临床特点及预后等分析,加深对药物性肝病的认识,为预防和早期治疗该病提供参考。方法采用回顾分析的方法对我院76例药物性肝病的住院患者进行研究。结果引起药物性肝病最主要的药物为中药制剂、抗结核药、抗生素、化疗药物、解热镇痛药及抗甲状腺功能亢进药物;一般在用药后1~4周内起病;临床主要表现以肝细胞型最为常见;早期发现后积极治疗多数预后良好;疗程3周至数月不等。结论药物性肝病尤其要注意中药制剂导致的肝病,主要以肝细胞型最为常见;早期发现、及时停用肝损害药物是治疗的前提;绝大部分药物性肝病预后良好,少数病例可发展为重症肝炎或肝硬化。
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| 关 键 词： | 药物性肝病 临床特点 回顾分析 |
Clinical features of 76 cases of drug-induced liver disease |
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| MAO Jingwei,TANG Haiying,WANG Yingde.Clinical features of 76 cases of drug-induced liver disease[J].Chinese Journal of Gastroenterology and Hepatology,2011,20(2):153-155. |
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| Authors: | MAO Jingwei TANG Haiying WANG Yingde |
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| Institution: | MAO Jingwei1,TANG Haiying2,WANG Yingde1 1.Department of Gastroenterology,2.Department of Respiratory,the First Affiliated Hospital of Dalian Medical University,Dalian 116011,China |
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| Abstract: | Objective To recognize and provide reference of preservation and early treatment of drug-induced liver disease through analyzing the cause,clinical features and prognosis.Methods All 76 patients of drug-induced liver disease were analyzed retrospectively.Results The main drugs which induced liver damage were Chinese drugs pharmaceutics,antituberculosis drugs,antibiotics,chemotherapeutics,antipyretic analgesic and anti-thyroid hyperfunction drugs.Theses drugs damaged the liver after administration 1 to 4 wee... |
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| Keywords: | Drug-induced liver disease Clinical features Retrospective analysis |
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