食管癌高发区的内镜普查研究

目的　通过内镜普查了解食管癌高发区人群食管及贲门癌和其他各级病变的分布情况。方法 :河北省肿瘤研究所于 2 0 0 1年 12月 - 2 0 0 2年 5月在河北省磁县进行了碘染色内镜普查 ,普查结果采用SPSS10 0处理。结果 :食管癌高发区人群中 ,轻、中、重度食管炎的组织学检出率分别是 34 9%、1 6 %、0 2 % ,基底细胞增生、轻、中、重度不典型增生的组织学检出率分别是 0 9%、8 6 %、7 8%、2 6 % ,原位癌、黏膜内癌、浸润性鳞癌的组织学检出率分别是 2 5 %、0 2 %、0 7% ;贲门黏膜非萎缩性胃炎、萎缩性胃炎的组织学检出率分别是 36 3%、11 5 % ,轻、重度不典型增生的组织学检出率分别是2 5 %、0 8% ,黏膜内腺癌、浸润性腺癌的组织学检出率分别是 0 1%、0 8% ;内镜普查食管癌的早期发现率为 79 4 % ,普查率达 73 8%。结论 :本次普查为食管及贲门早期癌的治疗及癌前病变的阻断治疗提供了组织学诊断 ,为今后提高食管癌、贲门癌的治愈率 ,降低食管癌、贲门癌的发病率及死亡率打下了基础

Endoscopic Screening of Esophageal Cancer in High Risk Areas

Objective To characterize the histologic types of esophageal cardiac cancer from endoscopic screening in high risk areas.Methods A endoscopic screening with Lugol's staining was carried out in Ci County from December 2001 to May 2002,and the data were input to the computer and handled by SPSS 10 0.Results The histologic detecting rates of mild esophagitis,moderate esophagitis,severe esophagitis in esophagus were 34 9%,1 6% and 0 2% respectively.The histologic detecting rates of basel cell hgperpl asia,mild dysplasia,moderate dysplasia,severe dysplasia in esophagus were 0 9%, 8 6%,7 8% and 2 6% respectively.The histologic detecting rates of carcinoma in situ,intramucosal carcinoma,Invasive squamous carcinoma in esophagus were 2 5%,0 2% and 0 7% respectively.The histologic detecting rates of non atrophic gastritis,atrophic gastritis in cardia were 36 3% and 11 5% respectively.The histologic detecting rates of mild dysplasia,severe dysplasia in cardia were 2 5% and 0 8% respectively.The histologic detecting rates of intramucosal adenocarcinoma,invasive adenocarcinoma in cardia were 0 1% and 0 8% respectively.The early detecting rate of esophageal cancer was 79 4%.The screening rate was 73 8%.Conclusions This study will contribute to early treatment of esophageal cardiac cancer and dysplasia,increasing the cure rates of esophageal cardiac cancer and decreasing the incidence rates and death rates of esophageal cardiac cancer.