| 人头发自由基检测在口腔颌面部恶性肿瘤诊断中的意义 |
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| 引用本文： | 陈纪伟,邱蔚六,何荣根,林国础,张志愿.人头发自由基检测在口腔颌面部恶性肿瘤诊断中的意义[J].上海口腔医学,1995,4(1):1-3. |
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| 作者姓名： | 陈纪伟 邱蔚六 何荣根 林国础 张志愿 |
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| 作者单位： | 上海第二医科大学附属第九人民医院颌面外科 |
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| 摘 要： | 作者应用电子自旋共振技术（ＥＳＲ）分别对正常人、口腔颌面部良恶性肿瘤、口腔粘膜病患者共３２４例的头发进行自由基测定，并与病理诊断相对照。结果表明，它们的阳性率分别为５．９％，６．１％，８４．５２％及９．１％。其中恶性肿瘤与正常人及良性肿瘤相比较，差别均较显著（Ｐ＜０．０１）。部分恶性肿瘤患者经治疗后，ＥＳＲ饱和功率点后移，上升到临界水准以上（＞１０．０ｍＷ），ＥＳＲ转阴。表明用ＥＳＲ早期诊断恶性肿瘤、追踪疗效具有一定临床价值。作者还结合检测资料对ＥＳＲ在监测肿瘤复发、监视白斑癌变等方面的意义进行了讨论。
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| 关 键 词： | 人头发自由基检测 口腔颌面部恶性肿瘤 诊断 电子自旋共振 ESR 自由基反应 |
The diagnosis value of malignant tumors in the Oral and Maxillofacial region using healthy person's free radical of hair] |
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| J W Chen,W L Qiu,R G He,G C Lin,Z Y Zhang.The diagnosis value of malignant tumors in the Oral and Maxillofacial region using healthy person''s free radical of hair][J].Shanghai Journal of Stomatology,1995,4(1):1-3. |
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| Authors: | J W Chen W L Qiu R G He G C Lin Z Y Zhang |
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| Institution: | Department of Oral and Maxillofacial Surgery,S Ninth People's Hospital. Shanghai 200011, China. |
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| Abstract: | Electron spin Resonance(ESR) was used to determine the free radical of hair from 324 cases.These cases included 185 healthy persons,33 benign tumor patients,84 malignant cases and 22 oral mucosa disease cases.The determined results were controlled with pathologic diagnosis to analyse the accordance. The result showed the positive rates of above mentioned cases were 5.9%,6.1%,84.52%and 9.1% respectively.The significant differences were observed when comparing the results of malignant cases with healthy person and benign tumor cases with healthy person and benign tumor cases(P<0.01).The ESR saturation power points of some malignant cases rose to above border-line(>10.0mW) after treatment.These results indicated using ESR to diagnosis early malignant cases and follow treatment effect possess certain clinical value. |
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