| 埃索美拉唑与奥美拉唑治疗内镜黏膜下剥离术术后并发症的对比观察 |
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| 引用本文： | 杨均,余建华,肖潇,孙文静,沈小春,傅鑫,邢寒阳,胡辂.埃索美拉唑与奥美拉唑治疗内镜黏膜下剥离术术后并发症的对比观察[J].重庆医学,2011,40(14):1397-1398. |
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| 作者姓名： | 杨均 余建华 肖潇 孙文静 沈小春 傅鑫 邢寒阳 胡辂 |
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| 作者单位： | 杨均,肖潇,孙文静,沈小春,傅鑫,邢寒阳,胡辂,Yang Jun,Xiao Xiao,Sun Wenjing,Shen Xiaochun,Fu Xin,Xing Hanyang,Hu Lu(第三军医大学大坪医院消化内科,重庆,400042);余建华,Yu Jianhua(重庆市綦江县人民医院内科,401420) |
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| 摘 要： | 目的观察埃索美拉唑与奥美拉唑治疗内镜黏膜下剥离术(ESD)术后并发症的疗效。方法随机双盲将41例行ESD治疗患者分为两组:A组20例,给予埃索美拉唑40 mg静脉注射,2次/日,疗程7 d,后序贯口服埃索美拉唑40 mg;B组21例,给予奥美拉唑静脉注射,2次/日,疗程7 d,序贯口服奥美拉唑40 mg。比较两组腹痛、创面溃疡愈合、消化道出血及不良反应情况。结果两组腹痛缓解的时间比较差异无统计学意义(P>0.05),创面愈合在7 d时埃索美拉唑组与奥美拉唑组比较,差异有统计学意义(P<0.05),14 d后A、B两组比较差异均无统计学意义(P>0.05),不良反应比较差异无统计学意义(P>0.05)。结论埃索美拉唑能更早促进ESD术后创面溃疡的愈合。
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| 关 键 词： | 奥美拉唑 手术后并发症 内镜黏膜下剥离术 上皮内瘤变 胃早癌 埃索美拉唑 |
Comparison of endoscopic submucosal dissection postoperative complications treated with esomeprazole and omeprazole |
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| Yang Jun,Yu Jianhua,Xiao Xiao,Sun Wenjing,Shen Xiaochun,Fu Xin,Xing Hanyang,Hu Lu.Comparison of endoscopic submucosal dissection postoperative complications treated with esomeprazole and omeprazole[J].Chongqing Medical Journal,2011,40(14):1397-1398. |
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| Authors: | Yang Jun Yu Jianhua Xiao Xiao Sun Wenjing Shen Xiaochun Fu Xin Xing Hanyang Hu Lu |
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| Institution: | Yang Jun1,Yu Jianhua2,Xiao Xiao1,Sun Wenjing1,Shen Xiaochun1,Fu Xin1,Xing Hanyang1,Hu Lu1(1.Department of Gastroenterology,Daping Hospital,Third Military Medical University,Chongqing 400042,China,2.Department of Internal Medicine,Qijiang County People's Hospital,Chongqing 401420,China) |
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| Abstract: | Objective To compare the therapeutic effect of the endoscopic submucosal dissection(ESD) postoperative complications treated with esomeprazole and omeprazole.Methods 20 patients with ESD were randomized to observation group with 21 cases and control group with 41 cases.The observation group was administered esomeprazole(40mg twice a day),omeprazole(40mg twice a day)for 7 d.The therapeutic effct of each drug such as auound surface healing and their symptoms such as stomachache,perforation and adverse reactio... |
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| Keywords: | omeprazole postoperative complications endoscopic submucosal dissection intraepithelial neoplasia early gastric cancer esoprazole |
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