| 大鼠海马CA1区锥体神经元树突分支的生后发育 |
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| 引用本文： | 王殿仕,吕顺艳,洪桢. 大鼠海马CA1区锥体神经元树突分支的生后发育[J]. 解剖学报, 2005, 36(1): 28-31 |
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| 作者姓名： | 王殿仕 吕顺艳 洪桢 |
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| 作者单位： | 第四军医大学解剖学教研室暨梁銶锯脑研究中心,西安,710032;第四军医大学生理学教研室,西安,710032 |
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| 基金项目： | 国家自然科学基金资助项目 (3 0 3 0 0 0 77)，第四军医大学“后备人才”基金资助 |
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| 摘 要： | 目的 研究大鼠海马CA1区锥体神经元树突分支的生后发育。方法 应用biocytin细胞内染色方法。结果 CA1锥体神经元的树突在生后第2～3周发育最快。顶树突的分支和长度在生后21d发育成熟；而基树突要到生后56～70d才发育成熟。基树突的发育较顶树突慢。结论 细胞内染色技术可更完整地显示神经元的形态。海马CA1区锥体神经元在出生后继续发育，且基树突的发育较顶树突慢。
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| 关 键 词： | 树突分支 生后发育 CA1 锥体神经元 大鼠 |
POSTNATAL DEVELOPMENT OF DENDRITIC ARBORIZATION IN RAT HIPPOCAMPAL CA1 PYRAMIDAL NEURONS |
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| WANG Dian-shi ,L Shun-yan+,HONG Zhen+. POSTNATAL DEVELOPMENT OF DENDRITIC ARBORIZATION IN RAT HIPPOCAMPAL CA1 PYRAMIDAL NEURONS[J]. Acta Anatomica Sinica, 2005, 36(1): 28-31 |
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| Authors: | WANG Dian-shi L Shun-yan+ HONG Zhen+ |
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| Affiliation: | WANG Dian-shi 1*,L Shun-yan+2,HONG Zhen+1 |
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| Abstract: | Objective To investigate the postnatal development of dendritic arborization in rat hippocampal CA1 pyramidal neurons. Methods Biocytin intracellular staining method was used in present study. Results The dendritic arborization of CA1 pyramidal neurons developed rapidly during the postnatal 2-3 weeks.The apical dendritic arborization reached the adult state at P21,whereas the basal dendritic arborization did not mature until P56-70.Furthermore,the basal dendrite developed significantly more slowly than the apical dendrite.Conclusion The neuronal morphology can be visualized much completely by intracellular staining method.The hippocampal CA1 pyramidal neurons continue to grow after birth,and the basal dendrite matures more slowly than the apical dendrite. |
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| Keywords: | Dendritic arborization Postnatal development CA1 Pyramidal neurons Rat |
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