Detection of type-specific antibodies to HSV-1 and HSV-2: comparative analysis of a chemiluminescence immunoassay with a conventional ELISA |
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| Authors: | Maters Amelia W Wright Christina V Lee Maria Teresa Schwichtenberg Greta Detrick Barbara |
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| Affiliation: | Immunology Laboratory, Department of Pathology, School of Medicine, Johns Hopkins University, Baltimore, MD 21287, USA. |
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| Abstract: | Type-specific serologic tests for human herpes simplex virus (HSV) are critically important for sexually transmitted disease evaluation. We compared the LIAISON® HSV-1 and HSV-2 Type Specific assays relative to an established commercial ELISA. The overall agreement of the chemiluminescence immunoassay versus the ELISA assay was 99.6% (HSV-1) and 100% (HSV-2). The LIAISON® methodology has several advantages. |
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| Keywords: | HSV-1 HSV-2 Serology Chemiluminescence ELISA |
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