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雄激素在失重骨丢失中的作用
引用本文:谈诚,张春林.雄激素在失重骨丢失中的作用[J].航天医学与医学工程,2004,17(4):309-312.
作者姓名:谈诚  张春林
作者单位:航天医学工程研究所,北京,100094;北京理工大学,北京,100081;北京理工大学,北京,100081
基金项目:总装备部试验技术重点课题(O1103301)
摘    要:临床研究已经证实雄激素在骨质疏松症病因学中具有重要的作用,但其在航天失重环境所导致骨量丢失中的作用仍然还不是十分清楚。本文就近年来有关失重引起机体中雄激素水平的变化,以及雄激素对骨质疏松的作用进行了综述。另外,对雄激素可能参与航天失重导致骨质丢失发生以及在预防和治疗中的作用也进行了探讨。

关 键 词:失重  雄激素  骨丢失  骨质疏松
文章编号:1002-0837(2004)04-0309-04

Effects of Androgen on the Bone Loss Induced by Weightlessness
TAN Cheng,ZHANG Chun-lin. Instiute of Space Medico-Engineering,Beijing ,China.Effects of Androgen on the Bone Loss Induced by Weightlessness[J].Space Medicine & Medical Engineering,2004,17(4):309-312.
Authors:TAN Cheng  ZHANG Chun-lin Instiute of Space Medico-Engineering  Beijing  China
Institution:TAN Cheng,ZHANG Chun-lin. Instiute of Space Medico-Engineering,Beijing 100094,China
Abstract:It has been proved clinically that androgen plays an important role in the etiology of osteoporosis. But it is still not clear whether it takes part in the bone loss induced by weightlessness during spaceflight. The purpose of this article is to discuss the change of androgen induced by weightlessness, and its role in the weightlessness induced-oesteoporosis. The mechanism of androgen in the pathogenesis of bone loss induced by weightlessness, and the possibility of its usage in prevention and therapy, were also discussed.
Keywords:weightlessness  androgen  bone loss  osteoporosis
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