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Acrodermatitis chronica atrophicans in an 11-year-old girl
Authors:R.R. MUELLEGGER  E.M. SCHLUEPEN  M.M. MILLNER  H.P. SOYER  M. VOLKENANDT  H. KERL
Affiliation:Department of Dermatology, Karl Franzens University, Auenbruggerplatz 8, A-8036 Graz, Austria;Department of Dermatology, Ludwig Maximilians University. Frauenlobstrasse 9-11, D-80337 Munich, Germany;Department of Paediatrics, Karl Franzens University, Auenbruggerplutz 30, A-8036 Graz, Austria
Abstract:Summary We report a case of acrodermatitis chronica atrophicans in an 11-year-old girl living in an area endemic for Lyme borreliosis. The diagnosis was first made on the basis of clinical, histopathological and serological findings. Moreover, Borrelia burgdorferi -specific DNA was amplified from lesional skin by polymerase chain reaction. Intravenous treatment with ceftriaxone (2g once daily) for 2 weeks was initiated. The skin changes clearly responded to the therapy, and Borrelia burgdorferi -specific gene segments were no longer detectable by polymerase chain reaction. This is the first report of molecular-proven acrodermatitis chronica atrophicans in childhood. The occurrence of this late skin manifestation of Lyme borreliosis in children is reviewed.
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