| 大鼠实验性牙齿移动过程中骨形成蛋白2的表达和意义 |
| |
| 引用本文： | 杨彤彤 米宇菁. 大鼠实验性牙齿移动过程中骨形成蛋白2的表达和意义[J]. 实用口腔医学杂志, 2005, 34(10): 824-826,i0001 |
| |
| 作者姓名： | 杨彤彤 米宇菁 |
| |
| 作者单位： | 山西医科大学第一医院 030001(杨彤彤)，山西医科大学第一医院 030001(米宇菁) |
| |
| 摘 要： | 目的探讨骨形成蛋白(BMP)超家族的成员BMP-2在大鼠正畸牙齿移动过程中牙周组织的分布和表达。方法用链霉亲和素生物素复合物(SABC)免疫组织化学法,检测实验性大鼠正畸牙齿移动过程中牙周组织BMP-2的表达。结果BMP-2在正畸牙齿加力各个时期存在特异的分布模式。正常牙周组织中主要分布于牙周膜,加力后张力区染色深,压力区为阴性。结论BMP-2参与了大鼠正畸牙齿移动骨改建过程,起非常重要的作用。
|
| 关 键 词： | 骨形成蛋白 正畸牙齿移动 免疫组织化学 大鼠 |
| 收稿时间： | 2005-07-12 |
| 修稿时间： | 2005-07-12 |
Distribution of bone morphogenetic protein-2 in periodontal tissue of rats during experimental orthodontic tooth movement |
| |
| YANG Tong-tong ,MI Yu-jing. Distribution of bone morphogenetic protein-2 in periodontal tissue of rats during experimental orthodontic tooth movement[J]. Journal of Practical Stomatology, 2005, 34(10): 824-826,i0001 |
| |
| Authors: | YANG Tong-tong MI Yu-jing |
| |
| Affiliation: | The First Hospital of Shanxi Medical University, Taiyuan 030001 ,China |
| |
| Abstract: | Objective To investigate the distribution and expression of bone morphogenetic protein-2 (BMP-2) in periodontic tissues during orthodontic tooth movement in rats.Methods BMP-2 expression was determined in the periodontial tissue during experimental orthodontic tooth movement in rats with immunohistochemical streptavidin biotin complex(SABC) method.Results BMP-2 expression had a specific pattern during orthodontic tooth movement.BMP-2 was mostly located in the periodontium.After being changed,the tension zone was intensely stained,while the pressure zone was poorly stained.Conclusion BMP-2 takes an important role in orthodontic tooth movement. |
| |
| Keywords: | Bone morphogenetic protein Orthodontic tooth movement Immunohistochemistry Rat |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
