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Outcome and prognostic factors of desmoplastic medulloblastoma treated within a multidisciplinary treatment concept |
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| Authors: | Stefan Rieken Timo Gaiser Angela Mohr Thomas Welzel Olaf Witt Andreas E Kulozik Wolfgang Wick Jürgen Debus Stephanie E Combs |
| Affiliation: | (1) Department of Radiation Oncology, University Hospital of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany;(2) Department of Neuropathology, University Hospital of Heidelberg, Im Neuenheimer Feld 220/221, 69120 Heidelberg, Germany;(3) Department of Pediatric Oncology, Hematology, Immunology, and Pneumonology, University Hospital of Heidelberg, Im Neuenheimer Feld 430, 69120 Heidelberg, Germany;(4) Department of Neurooncology, University Hospital of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany |
| Abstract: | BackgroundDesmoplasia in medulloblastoma is often diagnosed in adult patients and was repeatedly associated with improved results. Today, all medulloblastoma patients receive intensive multimodal treatment including surgery, radiotherapy and chemotherapy. This study was set up to investigate treatment outcome and prognostic factors after radiation therapy in patients with desmoplastic medulloblastomas. |
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