Xi Chen,Fei Liu,Bo Li,Yong-Gang Wei,Lv-Nan Yan,Tian-Fu Wen,Department of Liver and Vascular Surgery,West China Hospital,Sichuan University,37 Guo Xue Road,Chengdu 610041,Sichuan Province,China
Abstract:
AIM:To evaluate the association between p53 codon 72 polymorphism and liver cancer risk by means of meta-analysis. METHODS:Two investigators independently searched the Medline,Embase and Chinese Biomedicine databases.Summary odds ratios and 95%CI for p53 codon 72 polymorphism and liver cancer were calculated in fixedeffects model(Mantel-Haenszel method)and randomeffects model(DerSimonian and Laird method)when appropriate. RESULTS:This meta-analysis included 1115 liver cancer cases and 1778 controls.The comb...