| 外周T细胞淋巴瘤治疗新药普拉曲沙的药理及临床评价 |
| |
| 引用本文： | 戴一. 外周T细胞淋巴瘤治疗新药普拉曲沙的药理及临床评价[J]. 中国新药杂志, 2011, 0(2) |
| |
| 作者姓名： | 戴一 |
| |
| 作者单位： | 安徽新华学院药学院; |
| |
| 摘 要： | 普拉曲沙为首个治疗外周T细胞淋巴瘤(peripheral T-cell lymphoma,PTCL)药物,适用于复发或对其他化疗药物治疗无效的PTCL患者。本文通过检索文献,对普拉曲沙的作用机制、药动学、药理作用、临床评价及不良反应等方面进行了综述,为临床用药提供参考。
|
| 关 键 词： | 普拉曲沙 外周T细胞淋巴瘤 药理作用 临床评价 |
Pharmacology and clinical evaluation of pralatrexate for treatment of peripheral T-cell lymphoma |
| |
| DAI Yi. Pharmacology and clinical evaluation of pralatrexate for treatment of peripheral T-cell lymphoma[J]. Chinese Journal of New Drugs, 2011, 0(2) |
| |
| Authors: | DAI Yi |
| |
| Affiliation: | DAI Yi(School of Pharmaceutical Sciences of Anhui Xinhua College,Hefei 230088,China) |
| |
| Abstract: | Pralatrexate is the first drug for treatment of peripheral T-cell lymphoma(PTCL).It has been used in patients with recrudescence or without response to other chemotherapies.This review summarized its mechanisms of action,pharmacology,pharmacodynamics,clinical evaluation and adverse reactions in order to provide a reference for clinical medication. |
| |
| Keywords: | pralatrexate peripheral T-cell lymphoma(PTCL) clinical pharmacology clinical evaluation |
| 本文献已被 CNKI 等数据库收录！ |
