| 阿奇霉素相关房室传导阻滞 |
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| 引用本文： | 李英,徐峥,张海英,冯婉玉,公丕花.阿奇霉素相关房室传导阻滞[J].药物不良反应杂志,2014(3):176-177. |
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| 作者姓名： | 李英 徐峥 张海英 冯婉玉 公丕花 |
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| 作者单位： | [1]北京大学人民医院药剂科,100044 [2]北京大学人民医院呼吸内科,100044 |
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| 摘 要： | 1例86岁女性患者因肺部感染静脉滴注头孢曲松钠2.0 g（1次/d）、阿奇霉素0.5 g （1次/d）和盐酸氨溴索30 mg（2次/d）。第4次静脉滴注阿奇霉素约30 min时，患者突然出现胸闷、憋气。心电图示Ⅲ度房室传导阻滞。立即停止药物输注，给予吸氧。1h后，患者胸闷、憋气消失。5h 后复测心电图示窦性心律。未再应用阿奇霉素，患者未再出现类似症状。
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| 关 键 词： | 阿奇霉素 房室传导阻滞 |
Atrioventricular block related to azithromycin |
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| Li Ying,Xu Zheng,Zhang Haiying,Feng Wanyu,Gong Pihua.Atrioventricular block related to azithromycin[J].Adverse Drug Reactions Journal,2014(3):176-177. |
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| Authors: | Li Ying Xu Zheng Zhang Haiying Feng Wanyu Gong Pihua |
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| Institution: | ( Department of Pharmacy, Peking University People＇s Hospital, Beijing 100044, China Corresponding author： Zhang Haiying, Department of Pharmacy, Peking University People＇s Hospital, Belting 100044, China) |
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| Abstract: | An 86-year-old female patient with pulmonary infection was treated with IV infusions of ceftriaxone sodium 2. 0 g once daily,azithromycin 0. 5 g once daily,and ambroxol hydrochloride 30 mg twice daily. About 30 minutes after the fourth infusion of azithromycin,the patient abruptly developed chest tightness and suffocation. Electrocardiography showed Ⅲ degree atrioventricular block. Azithromycin was stopped immediately and she was treated with oxygen inhalation. One hour later,the symptoms of chest tightness and suffocation disappeared. Five hours later,a repeat electrocardiography showed sinus rhythm. Azithromycin was not given again and the similar symptoms did not recur any more. |
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| Keywords: | Azithromycin Atrioventricular block |
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