| 灵芝孢子对雄性糖尿病大鼠睾丸AGEs的影响 |
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| 引用本文： | 王柏欣,王淑秋,王景涛.灵芝孢子对雄性糖尿病大鼠睾丸AGEs的影响[J].黑龙江医药科学,2006,29(3):8-9. |
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| 作者姓名： | 王柏欣 王淑秋 王景涛 |
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| 作者单位： | 佳木斯大学基础医学院,黑龙江,佳木斯,154007;佳木斯大学基础医学院,黑龙江,佳木斯,154007;佳木斯大学基础医学院,黑龙江,佳木斯,154007 |
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| 摘 要： | 目的：观察灵芝孢子对雄性糖尿病大鼠睾丸AGEs的影响。方法：Wistar雄性大鼠50只，随机分成3组，应用链尿佐菌素（STZ）加高脂高糖饮食制备Ⅱ型糖尿病模型．灵芝组同时给予灵芝孢子粉，12周后检测睾丸组织AGEs变化。结果：Ⅱ型糖尿病模型制备成功，模型组睾丸组织AGEs显著高于正常组和灵芝组（P〈0．05）。结论：在糖尿病睾丸组织损伤中AGEs也是其中的因素。灵芝孢子粉对糖尿病大鼠睾丸组织具有保护作用。
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| 关 键 词： | Ⅱ型糖尿病 灵芝孢子 |
| 文章编号： | 1008-0104(2006)03-0008-01 |
| 修稿时间： | 2006年4月4日 |
Effect of the spores of Ganoderma lucidum on AGEs of NIDDM testicle in rat |
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| WANG Bai-xin,WANG Shu-qiu,WANG Jing-tao.Effect of the spores of Ganoderma lucidum on AGEs of NIDDM testicle in rat[J].Heilongjiang Medicine and Pharmacy,2006,29(3):8-9. |
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| Authors: | WANG Bai-xin WANG Shu-qiu WANG Jing-tao |
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| Abstract: | Objective: To observe the effects of the spores of Ganoderma lucidum on AGEs of the diabetic rat testicle.Methods: Fifty Wistar rats were divided into 3 groups at random.We established NIDDM rat model with streptozotocin(STZ) and high lipid,high glucose diet and detected testicle AGEs after administration of the spores of Ganoderma lucidum for 12 weeks.Results: The testicle AGEs from NIDDM group were higher than those from treated group(P<0.05).Conclusion: AGEs act as a factor in the damage to the testicle of diabetic rats.The spores of Ganoderma lucidum can protect the testicle of diabetic rats. |
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| Keywords: | NIDDM spores of Ganoderma lucidum |
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