Nuclear localization of beta-catenin involved in precancerous change in oral leukoplakia |
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| Authors: | Kosei Ishida Satoshi Ito Naoyuki Wada Hiroyo Deguchi Tsuyoshi Hata Masaru Hosoda Tsutomu Nohno |
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| Affiliation: | (1) Department of Oral Surgery, Kawasaki Medical School, Kurashiki 701-0192, Japan;(2) Department of Molecular and Developmental Biology, Kawasaki Medical School, Kurashiki 701-0192, Japan |
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| Abstract: | Background Oral leukoplakia is a precancerous change developed in the oral mucosa, and the mechanism that oral leukoplakia becomes malignant through atypical epithelium is not known. Here we compared the β-catenin expression detected by immunohistochemical staining in the normal oral epithelium and in the oral leukoplakia with or without dysplasia. |
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