Autologous 111In-oxine-labeled granulocytes in Yersinia infections

Autologous ¹¹¹In-oxine-labeled granulocytes have proved to be valuable for the localization of inflammatory bowel diseases, especially Crohn's disease and ulcerative colitis. Other rare inflammatory bowel diseases also yield positive ¹¹¹In scans. One case of Yersinia infection of the terminal ileum (Yersinia enterocolitica) showing an accumulation of ¹¹¹In-oxine-labeled granulocytes 0.5, 4, and 24 h after the reinjection of the labeled cells is described. The 4-day fecal excretion of ¹¹¹In-oxine granulocytes showed a slight inflammatory activity of the terminal ileum. One negative scan is reported in a cotrimoxazoletreated patient with Yersinia infection.