急性重症胰腺炎Binder综合评分及其预后

目的 了解急性重症胰腺炎(SAP)器官功能或代谢合并症Binder评分与SAP预后的关系。方法 对我院收治的112例SAP回顾调查，根据Binder积分和SAP并发症如休克、ARDS、胰性脑病和全身感染发生率与SAP死亡的关系，估计SAP的预后。结果 SAPll2例，治愈92例(82．1％)，死亡20例，病死率为17．8％，发生各种并发症73例(65．2％)。ARDS、休克、胰性脑病和全身感染，其病死率分别为6．3％、7．1％、5．3％和3．5％。按SAP器官或代谢合并症综合评分大于7分(或等于)组和评分小于7分组，综合评分大于7分组病死率非常显著高于评分小于7分组(P＜0．01)。结论 休克、ARDS、胰性脑病和全身感染是SAP主要并发症和死亡原因。Binder积分高低与其有关，积分越高，SAP预后越差，Binder评分高低不仅可以判定SAP病情轻重，而且估计SAP的预后。

Relationship between Binder's point and prognosis of severe acute pancreatitis

Objective To investigate the relationship between Binder point and prognosis of severe acute pancreatitis (SAP). Methods The clinical data of 112 patients with SAP treated in our hospital in the past 19 years were retrospectively analyzed. Its prognosis was estimated based on the analysis of the relationship between death from SAP and Binder point and such complications as shock, ARDS, pancreatic brain disease and systemic infection etc. Results Of the 112 patients, 92 (82.1%) were cured and 20 died (17.8%). Seventy-three patients (65.2%) had complications. The rates of complications related to mortality of ARDS, shock, pancreatic brain disease and systemic infection were 6.3%, 7.1%, 5.3% and 3.5%, respectively. The patients were divided into above-7-point group and below-7-point group by the composite points based on the organic function failure or diabetic complications. The difference of mortality between the 2 groups was significant (P<0.01). Conclusions Shock, ARDS, pancreatic brain disease and systemic infection are the main complications of SAP and major reasons for death. Binder point is correlated to these complications. The higher the point, the worse the prognosis.