| 大承气汤及大黄治疗小鼠细菌性腹膜炎 |
| |
| 引用本文： | 胡萍,白凤菊,李东升,张才丽,吴咸中. 大承气汤及大黄治疗小鼠细菌性腹膜炎[J]. 中国中西医结合杂志, 2000, 20(1): 53-54 |
| |
| 作者姓名： | 胡萍 白凤菊 李东升 张才丽 吴咸中 |
| |
| 作者单位： | 中国协和医科大学!博士研究生(胡萍)，天津医科大学药理教研室!天津300070(白凤菊，李东升，张才丽)，天津市中西医结合急腹症研究所(吴咸中) |
| |
| 基金项目： | 天津市八五攻关项目! (No .92 0 0 9380 1 2 ) |
| |
| 摘 要： | 目的 研究腹腔注射大承气汤或其组分大黄对小鼠抗菌能力的影响。方法 于建立细菌性腹膜炎模型前分别腹腔注射大承气汤或大黄煎对小鼠预防治疗２天后，分别腹腔注射大肠杆菌（１０＾８／ｍｌ）或变形杆菌（１０＾６／ｍｌ）建立腹膜炎模型，再继续用药治疗２天。结果 模型的治疗组小鼠死亡数及相应菌血症发生率明显低于对照组（Ｐ〈０．０５），大承气汤和大黄煎对大肠杆菌和变形杆菌感染的小鼠均有良好保护作用。预防加治疗组和模
|
| 关 键 词： | 大承气汤 大黄 细菌性腹膜炎 中医药疗法 腹膜炎 |
Treatment of Bacterial Peritonitis with Dachengqi Decoction and Rhubarb in Mice |
| |
| HU Ping,BAI Fengju,LI Dongsheng,et al. Treatment of Bacterial Peritonitis with Dachengqi Decoction and Rhubarb in Mice[J]. Chinese journal of integrated traditional and Western medicine, 2000, 20(1): 53-54 |
| |
| Authors: | HU Ping BAI Fengju LI Dongsheng et al |
| |
| Abstract: | Objective: To observe the antiseptic effect of Dachengqi Decoction (DCQD) or rhubarb, one of the ingredients of DCQD in mice. Methods: The model mice were established by peritoneal injection of Escherichia coli (10 8/ml) or Proteus vulgaris (10 6/ml) respectively. DCQD or rhubarb was given from 2 days before to 2 days after modelling for preventing and treating. Results: The mortality and bacteremia occurrence of the treatment group were significantly lower than those of the control group (P<0 05). Both DCQD and rhubarb showed protective effect on Escherichia. coli or Proteus vulgaris infection in mice. The cardiac blood smear and culture of survival mice in prevention plus treatment group and model group showed negative (bacteria) results but those of dead mice showed positive result. Conclusion: DCQD and rhubarb have excellent bactericidal effect. |
| |
| Keywords: | Dachengqi Decoction rhubarb bacterial peritonitis |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
| 点击此处可从《中国中西医结合杂志》浏览原始摘要信息 |
|
点击此处可从《中国中西医结合杂志》下载免费的PDF全文 |
