绵阳市不同地区男男性行为者HIV/梅毒感染及影响因素分析

摘要:目的　了解四川省绵阳市不同地区男男性行为者（MSM）艾滋病病毒（HIV）/梅毒感染现状，分析影响因素。方法　2013年4-10月，以绵阳市辖区所有9个县（市、区）MSM为对象，在固定场所知情同意下，应用滚雪球抽样法，进行调查对象招募和自填式匿名行为学调查及生物学检测。结果　共调查861例，HIV确证阳性29例，阳性率3.8%；梅毒阳性15例，感染率2.2%；不同地区差异有统计学意义（分别有χ2＝15.035、20.361，分别有P＝0.035、0.002）。多因素分析结果，年龄≥30岁（OR＝2.766）、户籍外省（OR＝4.348）、地区涪城区/江油市（OR＝2.527）、近6月肛交无保护性（OR＝3.104）、寻找性伴场所浴室/家庭型（OR＝2.825）、近1年诊断过性病（OR＝4.630）是HIV感染，年龄≥30岁（OR＝3.744）、近6月肛交无保护性（OR＝5.464）、近1年诊断过性病（OR＝27.778）是梅毒感染有统计学意义的危险因素（均有P＜0.01或P＜0.05）。结论　绵阳市MSM人群 HIV/梅感染仍处于较高水平，地区差异明显。感染风险与人口学特征、性行为和性病感染相关，应针对性开展行为干预。

Analysis of influencing factors for HIV/syphilis in MSM from different regions of Mianyang city

Abstract: Objective The aim of this study was to find out the current situation and analyze the influencing factors for human immunodeficiency virus (HIV) /syphilis among men who have sex with men (MSM) in Mianyang. Methods MSM in all nine counties (cities, districts) in Mianyang were chosen as the object in a fixed place of informed consent from April to October 2013. The snowball sampling method was applied, the survey of recruitment and self-administered anonymous surveys as well as biological detection were conducted. Results Among the 861 cases, 29 HIV-positive cases were confirmed with a positive rate of 3.8%, while 15 cases of syphilis-positive infection were reported with a rate of 2.2%. There were significant differences in different regions (χ2=15.035, 20.361; P=0.035, 0.002, respectively). Multi-factors analysis showed that risk factors for HIV infection were age ≥30 years old (OR=2.766), household provinces (OR=4.348), area of Fucheng district/Jiangyou (OR=2.527), not using condom in anal sex in the lastest six months (OR=3.104), looking for partner sites as bathroom/family type (OR=2.825), diagnosis of sexually transmitted diseases over the past one year (OR=4.630). Risk factors for syphilis infection were age ≥30 years old (OR=3.744), not using condom in anal sex in the lasts six months (OR=5.464), diagnosis of sexually transmitted diseases over the past one year (OR=27.778) (Both P<0.01 or P<0.05). Conclusion The HIV/Syphilis infection rate in MSM from Minayang was relatively high, with significant regional differences. The risk of infection was related with demographic characteristics, sexual behavior and STD infection. It should be targeted to carry out the behavior intervention.