2013年度贵州省发热呼吸道症候群病毒感染状况调查

摘要:目的　了解贵州省发热呼吸道症候群病毒性疾病的感染状况。方法　调查贵州省2013年度发热呼吸道症候群病例432例，采集呼吸道标本421份，通过相应试剂盒提取核酸，进行实时荧光定量（Real-Time）PCR检测流感病毒、副流感病毒、冠状病毒、呼吸道合胞病毒、腺病毒、博卡病毒，鼻病毒及偏肺病毒。结果　从421份标本中检测出阳性标本128份，阳性率为30.41%。其中流感病毒60份，阳性率为14.25%；冠状病毒8份，阳性率为1.90%；博卡病毒3份，阳性率为0.71%；腺病毒10份，阳性率为2.38%；偏肺病毒9份，阳性率为2.14%；鼻病毒38份，阳性率为9.03%；未检出呼吸道合胞病毒和副流感病毒。检出3例流感病毒和鼻病毒混合感染。结论　呼吸道病毒是导致发热呼吸道症候群的重要病原体，其中以流感病毒最为常见，鼻病毒其次，腺病毒、偏肺病毒等检出率较低。

Survey on the infection status of febrile respiratory syndrome virus infection in Guizhou province

Abstract: Objective The aim of this study was to further understand the infection status of febrile respiratory syndrome virus infection in Guizhou province. Methods The survey of febrile respiratory syndrome in 432 cases of respiratory tract was conducted in 2013 Guizhou. Four hundred and twenty-one samples were collected through the corresponding reagent kit for extracting nucleic acid and real-time fluorescence quantitative PCR detection (Real-Time). Detection of influenza virus, human parainfluenza virus, human coronavirus, respiratory syncytial virus, respiratory adenovirus, human bocavirus, rhinovirus and human metapneumovirus was performed. Results Among the tested 421 specimens, 128 specimens were positive, and the positive rate was 30.41%. There were 60 influenza virus, and the positive rate was 14.25%. There were eight human coronavirus, and the positive rate was 1.90%. There were three human bocavirus, and the positive rate was 0.71%. There were ten respiratory adenovirus, and the positive rate was 2.38%. There were nine human metapneumovirus, and the positive rate was 2.14%. There were 38 rhinovirus, and the positive rate was 9.03%. No human parainfluenza virus and respiratory syncytial virus was detected. Three cases were mixed infection of influenza virus and rhinovirus. Conclusion Respiratory viruses was important pathogens and the leading cause of febrile respiratory syndrome. Influenza viruses were the most common, followed by rhinovirus, while respiratory adenovirus and others were relatively rare.