乌鲁木齐市1～14岁维、汉儿童乙肝疫苗接种率 与乙肝病毒携带状况调查

摘要:目的　比较乌鲁木齐市1～14岁维、汉儿童乙肝疫苗接种率与乙肝病毒携带状况。方法　采取整群随机抽样的方法，共调查1～14岁儿童1229人。结果　l～14岁儿童乙肝疫苗接种率、首针及时接种率、全程接种率和抗-HBs阳性率汉族均高于维吾尔族。维、汉儿童乙肝疫苗接种率分别为79.39%、96.63%；首针及时接种率分别为73.77%、91.52%；全程接种率分别为74.71%、96.26%；抗-HBs阳性率分别为58.66%、74.45%；HBsAg阳性率分别为2.34%、0.50%。维、汉2个民族的儿童上述指标差异均有统计学意义。结论　1～14岁维、汉儿童HBsAg阳性率和抗-HBs阳性率均有统计学差异，主要与乙肝疫苗接种率、首针及时接种率和全程接种率有关。需进一步加强维吾尔族儿童乙肝疫苗免疫接种工作。

Investigation on HBV carrying status and hepatitis B vaccine inoculation rate among children at the age from one to 14 among Uygur and Han in Urumqi

Abstract: Objective The aim of this study was to compare HBV coverage and hepatitis B vaccine inoculation rate among children at the age from one to 14 among Uygur and Han in Urumqi. Methods By cluster randomize sampling, 1229 children at the age from one to 14 were selected from seven districts and one county. Results The hepatitis B vaccine inoculation rate, timely-birth dose inoculation rate, hepatitis B vaccine inoculation rate for the whole vaccination course and positive rate of anti-HBs among children at the age from one to 14 in Han were higher than those in Uygur. And the rates all showed significant differences between Uygur with Han children. The hepatitis B vaccine inoculation rates for Uygur children and Han children were 79.39% and 96.63%, timely-birth dose inoculation rates were 73.77% and 91.52%, hepatitis B vaccine inoculation rates for the whole vaccination course were 74.71% and 96.26%, the positive rates of anti-HBs were 58.66% and 74.45%, the positive rates for HBsAg were 2.34% and 0.50%. And these variables all had significant differences between Uygur children and Han children. Conclusion The positive rates of HBsAg and anti-HBs among children at the age from one to 14 all showed significant differences between Uygur with Han children, mainly effected by the hepatitis B vaccine inoculation rate, timely-birth dose inoculation rate and whole course hepatitis B vaccine inoculation rate. It is necessary to strengthen the HBV vaccine inoculation for the Uygur children.