艾滋病合并弓形虫感染研究进展

摘要:弓形虫（Toxoplasma gondii）是一种专性细胞内寄生的机会致病原虫，引起严重的人兽共患弓形虫病。在机体免疫功能正常情况下，弓形虫多为隐性感染，而在免疫缺陷人群如艾滋病患者，弓形虫可对患者的中枢神经系统、呼吸系统、消化系统、内分泌系统、心血管系统等产生不同程度的损害。艾滋病合并弓形虫感染的研究主要集中在流行病学调查和诊断方法、对机体的影响、动物模型研究和治疗药物等方面，本文就艾滋病合并弓形虫感染研究进展进行综述。

A review of AIDS with Toxoplasma gondii co-infection

Abstract: Toxoplasma gondii is an obligate intracellular protozoan parasite that causes toxoplasmosis, a zoonotic parasitic disease. Toxoplasma gondii infection is usually asymptomatic in immunocompetent individuals, but maycause diseases in immune- compromised patients, such as AIDS patients. Toxoplasma gondii produces different degrees of damage to the central nervous system, respiratory system, digestive system, endocrine system and cardiovascular system of patients. Research on Toxoplasma gondii infection so far has been focused on the seroepidemiological investigation, diagnosis methods, effect on organism, animal model construction, therapeutic drug screening and so on. This paper reviewed recent advances of research on toxoplasmosis of HIV/AIDS patients.