| 体外受精失败后行单精子卵胞浆内注射获成功妊娠分娩 |
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| 引用本文： | 刘芸,许雪峰,何凌云.体外受精失败后行单精子卵胞浆内注射获成功妊娠分娩[J].福州总医院学报,2008(4). |
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| 作者姓名： | 刘芸 许雪峰 何凌云 |
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| 作者单位： | 福州总医院妇产科; |
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| 摘 要： | 目的:探讨常规体外受精-胚胎移植(IVF-ET)受精失败后,对未受精卵母细胞进行补救性单精子卵胞浆内注射(ICSI)治疗的可行性和安全性。方法:超促排卵获得的卵子进行常规体外受精,16小时后对全部或>70%卵母细胞未受精的病例,进行补救ICSI,所获得的优质胚胎进行宫腔内移植。结果:7例患者51枚未受精卵母细胞行补救ICSI后,受精37枚,卵裂30枚,优质胚胎17个,受精率72.5%,卵裂率81%,与20例单纯行ICSI治疗者比较,受精率、卵裂率无统计学显著性差异。补救ICSI组1例获临床妊娠,并分娩健康新生儿,随访1年余未发现异常,临床妊娠率(14.3%)较单纯ICSI组(35%)显著降低(P<0.01)。结论:常规体外受精-胚胎移植受精失败后,对未受精卵母细胞进行补救性ICSI,有机会获得健康新生儿。
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| 关 键 词： | 体外受精-胚移植 单精子卵胞浆内注射 补救 |
LIVE BIRTH AND NORMAL OFFSPRING AFTER TRANSFER OF EMBRYOS FROM RESCUE INTRACYTOPLASMIC SPERM INJECTION. |
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| Liu Yun,Xu Xue-feng,He Ling-yun.LIVE BIRTH AND NORMAL OFFSPRING AFTER TRANSFER OF EMBRYOS FROM RESCUE INTRACYTOPLASMIC SPERM INJECTION.[J].Journal of Fuzhou Genenal Hospital,2008(4). |
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| Authors: | Liu Yun Xu Xue-feng He Ling-yun |
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| Institution: | Liu Yun,Xu Xue-feng,He Ling-yun. Department of Gynecology,Fuzhou general hospital,Fujiang Fuzhou,350025. |
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| Abstract: | Objective:To investigate the feasibility and security of rescue intracytoplasmic sperm injection(ICSI) after complete fertilization failure during in vitro fertilization(IVF) cycle.Method:Unfertilized oocytes from IVF cycles with completely or almost completely fertilization failure were performed reinsemination by ICSI 16 h after initial insemination.Fertilization and cleavage rates,embryo quality and pregnancy rates after rescue ICSI were the main outcome measures.There results were compared with those of... |
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| Keywords: | in vitro fertilization intracytoplasmic sperm injection rescue |
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